Michelle Winn, M.D.

Post-Doctoral Fellow

Michelle Winn was a graduate of the North Carolina School of Science and Mathematics and received a BS in biology from the University of North Carolina at Chapel Hill in 1988. She received an MD from the Brody School of Medicine in Greenville, NC in 1992. She completed her Residency in Internal Medicine and Psychiatry and her Nephrology Fellowship at Duke.

Durham, North Carolina

Duke University Medical Center

Lay Summary of the Project:

Dr. Gbadegesin and Dr. Winn collaborated at the Duke Center for Human Genetics where they examined the genes of more than 100 families in which many members have FSGS. They sequenced and analyzed genes to find the specific locations or ‘loci’ of a gene or DNA sequence on a chromosome associated with FSGS and the risk factors associated with FSGS disease progression. While the cause of FSGS remains unknown, recent advances in the field of molecular genetics have shown that a defect in genes encoding a component of the kidney filtering mechanism may be responsible for some cases.


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