Michael Janech, Ph.D.
NephCure Young Investigator Awardee
Janech, PhD, is the Assistant Professor in the Division of Nephrology and Associate Director of the Nephrology Proteomic Laboratory at the Medical University of South Carolina. He earned a Bachelor of Science in Biology from Oakland University, a Master of Science in Marine Biology from the College of Charleston and a Ph.D. in Molecular and Cellular Biology from the Medical University of South Carolina. Janech plans to discover urine biomarkers which will better characterize glomerular diseases. Results from these studies will form the basis for early detection of glomerular disease to prevent progression to end-stage renal disease.
Charleston, South Carolina
Medical University of South Carolina
Lay Summary of the Project:
Currently, the primary causes of NS (Minimal Change Disease, FSGS, and Membranous Nephropathy) can only be conclusively identified with a kidney biopsy. However, biopsies are not always accurate, especially among patients with FSGS because the disease process is found only in segments of the tissue. Dr. Janech is working to discover urine biomarkers as a non-invasive method to diagnose kidney diseases. A urine biomarker could also allow for earlier detection and possible prevention.