The FIRSTx Clinical Trial May 18, 2018 by Kylie Karley About the FIRSTx Clinical Trial FIRSTx is a Phase 2 study testing the safety and effectiveness of an investigational drug called CXA-10 designed to treat FSGS without steroids. This study will see if CXA-10 can reduce proteinuria while maintaining stable kidney function in people with FSGS. Throughout the course of the study, researchers will measure how different doses of CXA-10 impact proteinuria and carefully evaluate the kidney related and other effects of CXA-10. The study is taking place at approximately 20 centers across the United States. How To Contact a Study Center: Call 844-618-2479 Click here for study website Email FIRSTx_Trial@med.umich.edu About CXA-10 Animal studies suggest that CXA-10 appears to work by reducing inflammation in the glomeruli and helping to prevent scarring. CXA-10 has been evaluated in healthy volunteers. CXA-10 will be provided to study participants in the form of a pill taken once a day in the morning with food. Learn more about The FirstX Clinical Trial by clicking here. Click here to learn more about research and clinical trials Check out recent Research News