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Exploring Treatment Options:

The decision to prescribe a medication is the responsibility of your physician/primary care provider based on his/her evaluation of your condition. The below is meant for informational purposes only. Discuss this information and all information about drugs/medications with your physician before starting OR stopping any medication.Successful-withdrawal-of-drug-after-family-kidney-transplant-250x158

Goals of treatment:

Short term

  • Stop protein in urine (“repair” glomeruli)
  • Normalize clinical symptoms (swelling, tiredness) and blood changes (plasma proteins, high cholesterol)

Long term

  • Prevent recurrences of protein in urine
  • Prevent  deterioration of kidney function

Treatment Information – find answers to frequently asked questions about the following:

  • Prednisone
  • Acthar
  • Rituximab (rituxan)
  • Cyclophosphamide (Cytoxan)
  • Mycophenalate Mofetil (CellCept, Myfortic)
  • ACE Inhibitors
  • Angiotensin II Receptor Blockers (ARBs)
  • Cyclosporine
  • Tacrolimus (Prograf)
  • Sirolimus (Rapamune)
  • Liposorber LA-15®
  • Clinical Trials

The decision to change or stop current medication is usually based on the following:

  • Complete remission – partial remission: proteinuria less than 3.5g
  • Permanent
  • Temporary
  • Recurrence (relapse)
  • Steroid-sensitive: patient experiences reduced protein loss in urine
  • Steroid-dependent: patient experiences reduced protein loss in urine, but cannot go off the medication without relapsing
  • No response
  • Trial of other medications will begin
  • Kidney function deterioration

Our Mission

NephCure Kidney International’s ® mission is to accelerate research for effective treatments for rare forms of Nephrotic Syndrome, and to provide education and support that will improve the lives of those affected by these protein-spilling kidney diseases.

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