{"id":28275,"date":"2023-12-13T17:44:17","date_gmt":"2023-12-13T22:44:17","guid":{"rendered":"https:\/\/nephcure.org\/globalcollaborationatparasolproject-fsgs-clinicaltrials-newtreatmentoptions\/"},"modified":"2024-05-01T16:28:16","modified_gmt":"2024-05-01T20:28:16","slug":"colaboracionglobalenproyectoparasolfsgsensayosclinicosnuevasopcionesdetratamiento","status":"publish","type":"post","link":"https:\/\/nephcure.org\/es\/globalcollaborationatparasolproject-fsgs-clinicaltrials-newtreatmentoptions\/","title":{"rendered":"La colaboraci\u00f3n global en el proyecto PARASOL mejora los ensayos cl\u00ednicos de FSGS y la esperanza de nuevas opciones de tratamiento"},"content":{"rendered":"<p style=\"font-weight: 400;\"><img loading=\"lazy\" decoding=\"async\" class=\"alignright wp-image-9748 size-medium\" src=\"https:\/\/nephcure.org\/wp-content\/uploads\/2024\/04\/MicrosoftTeams-image-1-scaled.jpg\" alt=\"\" width=\"300\" height=\"225\" \/>El 9 de diciembre de 2023, investigadores, m\u00e9dicos, reguladores y pacientes de todo el mundo se reunieron en Washington, DC en el Proyecto Proteinuria and GFR as Clinical Trial Endpoints in Focal Segmental Glomerulosclerosis (PARASOL) para discutir el desarrollo de modelos bioestad\u00edsticos que podr\u00edan ayudar con la dise\u00f1o de ensayos cl\u00ednicos y ayuda a la posterior aprobaci\u00f3n regulatoria de nuevos tratamientos para FSGS.<\/p>\n<p style=\"font-weight: 400;\"><a href=\"https:\/\/nephcure.org\/es\/livingwithkidneydisease\/ns-and-other-glomerular-diseases\/understanding-fsgs\/\">FSGS<\/a> Es una enfermedad dif\u00edcil de estudiar debido a la diversa poblaci\u00f3n de pacientes que experimenta diferentes s\u00edntomas, respuesta a los tratamientos y tasas de progresi\u00f3n.<\/p>\n<p style=\"font-weight: 400;\"><img loading=\"lazy\" decoding=\"async\" class=\"size-medium wp-image-9749 alignleft\" src=\"https:\/\/nephcure.org\/wp-content\/uploads\/2024\/04\/MicrosoftTeams-image-2-scaled.jpg\" alt=\"\" width=\"225\" height=\"300\" \/><\/p>\n<p style=\"font-weight: 400;\">Dos cosas importantes que miden los m\u00e9dicos son las prote\u00ednas en la orina (<a href=\"https:\/\/nephcure.org\/es\/livingwithkidneydisease\/proteinuria-resource-center\/what-is-proteinuria\/\">proteinuria<\/a>) y la funci\u00f3n renal (eGFR). Pero estos pueden fluctuar mucho en FSGS. En esta reuni\u00f3n, el grupo discuti\u00f3 c\u00f3mo tener en cuenta esta variabilidad en sus modelos estad\u00edsticos del curso de la enfermedad.<\/p>\n<p style=\"font-weight: 400;\">Los asistentes al proyecto PARASOL tambi\u00e9n consideraron qu\u00e9 resultados deber\u00edan predecir los modelos, como la insuficiencia renal. Vincular los cambios en la proteinuria o la TFG con estos resultados podr\u00eda ayudar a identificar nuevos tratamientos m\u00e1s r\u00e1pidamente.<\/p>\n<p style=\"font-weight: 400;\">\u201cReconocemos la necesidad urgente de enfoques adicionales innovadores para estudiar FSGS. Mientras navegamos por las complejidades de esta desafiante enfermedad, la colaboraci\u00f3n entre expertos globales es clave. Al desarrollar modelos matem\u00e1ticos precisos, nuestro objetivo no solo es clasificar los grupos de pacientes de manera m\u00e1s efectiva, sino tambi\u00e9n predecir mejor resultados como la insuficiencia renal. Todo el equipo de PARASOL est\u00e1 comprometido a proporcionar a las agencias reguladoras y a las compa\u00f1\u00edas farmac\u00e9uticas herramientas factibles y basadas en datos para mejores ensayos cl\u00ednicos y pruebas de nuevas terapias FSGS\u201d, dijo Josh Tarnoff, director ejecutivo de NephCure.<img loading=\"lazy\" decoding=\"async\" class=\"size-medium wp-image-9750 alignright\" src=\"https:\/\/nephcure.org\/wp-content\/uploads\/2024\/04\/MicrosoftTeams-image-3-scaled.jpg\" alt=\"\" width=\"300\" height=\"225\" \/><\/p>\n<p style=\"font-weight: 400;\">Los participantes acordaron que para lograr estos objetivos, necesitar\u00edan reunir conjuntos de datos de investigaci\u00f3n de todo el mundo para asegurarse de que los modelos funcionen para todos los pacientes con GEFS. Al revisar los datos, esperan tomar decisiones para comenzar a construir modelos iniciales.<\/p>\n<p style=\"font-weight: 400;\">Sus modelos pretenden proporcionar una herramienta pr\u00e1ctica para que las compa\u00f1\u00edas farmac\u00e9uticas dise\u00f1en <a href=\"https:\/\/kidneyhealthgateway.com\/trials-research\/\">ensayos cl\u00ednicos<\/a> que podr\u00eda probar nuevas terapias FSGS y mejorar las opciones para los pacientes.<\/p>\n<p style=\"font-weight: 400;\">El proyecto PARASOL est\u00e1 patrocinado por NephCure, la Sociedad Internacional de Enfermedades Glomerulares, la Fundaci\u00f3n Nacional del Ri\u00f1\u00f3n y la Iniciativa de Salud Renal.<\/p>\n<p style=\"font-weight: 400;\">Hay planes para que investigadores y m\u00e9dicos asistan a un proyecto PARASOL de seguimiento en junio de 2024 y presenten los resultados del proyecto en el proyecto de la Sociedad Estadounidense de Nefrolog\u00eda a fines de 2024.<\/p>\n<p>Si desea involucrarse m\u00e1s en el proyecto PARASOL o tiene preguntas adicionales, dirija todas sus consultas a <a href=\"mailto:info@nephcure.org\">info@nephcure.org<\/a>.<\/p>","protected":false},"excerpt":{"rendered":"<p>El 9 de diciembre de 2023, investigadores, m\u00e9dicos, reguladores y pacientes de todo el mundo se reunieron en Washington, DC en el evento Proteinuria and GFR as Clinical Trial Endpoints in Focal Segmental Glomerulosclerosis... <a title=\"La colaboraci\u00f3n global en el proyecto PARASOL mejora los ensayos cl\u00ednicos de FSGS y la esperanza de nuevas opciones de tratamiento\" class=\"read-more\" href=\"https:\/\/nephcure.org\/es\/globalcollaborationatparasolproject-fsgs-clinicaltrials-newtreatmentoptions\/\" aria-label=\"Leer m\u00e1s sobre La colaboraci\u00f3n global en el proyecto PARASOL mejora los ensayos cl\u00ednicos de FSGS y la esperanza de nuevas opciones de tratamiento\">Leer m\u00e1s<\/a><\/p>","protected":false},"author":222,"featured_media":28279,"comment_status":"open","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"inline_featured_image":false,"footnotes":""},"categories":[354],"tags":[374,462,362,463,464,465,466,468,469],"disease-category":[],"resource-type":[260],"treatment-option":[],"hf_cat_post":[],"class_list":["post-28275","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-recent-news","tag-clinical-trials","tag-fda-treatments","tag-fsgs","tag-fsgs-therapies","tag-gfr","tag-kidney-failure","tag-parasol","tag-porteinuria","tag-rare-kidney-disease-news","resource-type-news"],"acf":[],"yoast_head":"<!-- This site is optimized with the Yoast SEO Premium plugin v27.5 (Yoast SEO v27.7) - https:\/\/yoast.com\/product\/yoast-seo-premium-wordpress\/ -->\n<title>Global Collaboration at PARASOL Project Enhances FSGS Clinical Trials and Hope of New Treatment 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