{"id":34794,"date":"2024-12-05T16:01:28","date_gmt":"2024-12-05T21:01:28","guid":{"rendered":"https:\/\/nephcure.org\/?page_id=34794"},"modified":"2025-12-11T08:29:15","modified_gmt":"2025-12-11T13:29:15","slug":"complemento-3-glomerulopatia-c3g-ic-mpgn-3","status":"publish","type":"page","link":"https:\/\/nephcure.org\/es\/intro-to-rkd\/types-of-rkd\/ic-mpgn\/","title":{"rendered":"Glomerulonefritis membranoproliferativa por complejos inmunes (GNMP-IC)"},"content":{"rendered":"<section class=\"gb-container gb-container-ba2e2dcb\">\n<div class=\"yoast-breadcrumbs breadcrumb\"><span><span><a href=\"https:\/\/nephcure.org\/\">Home<\/a><\/span> \/ <span><a href=\"https:\/\/nephcure.org\/intro-to-rkd\/\">Intro to RKD<\/a><\/span> \/ <span><a href=\"https:\/\/nephcure.org\/intro-to-rkd\/types-of-rkd\/\">Types of RKD<\/a><\/span> \/ <span class=\"breadcrumb_last\" aria-current=\"page\">Immune Complex Membranoproliferative Glomerulonephritis (IC-MPGN)<\/span><\/span><\/div>\n\n<div class=\"gb-container gb-container-80071c84 hero-copy\">\n\n<h1 class=\"gb-headline gb-headline-6cf43bd0 gb-headline-text hero-content\"><strong>Immune Complex Membranoproliferative Glomerulonephritis (IC-MPGN) <\/strong><\/h1>\n\n\n\n<p class=\"hero-p wp-block-paragraph\">Immune Complex Membranoproliferative Glomerulonephritis (IC-MPGN or MPGN) is a disease that causes inflammation and injury to the glomeruli. The glomeruli are tiny filtering units in the kidneys that help remove toxins from the blood.&nbsp;<\/p>\n\n\n\n<p class=\"hero-p wp-block-paragraph\">MPGN happens when antibodies and antigens form &#8220;immune complexes&#8221; that activate part of the immune system called \u201cthe complement system\u201d\u00a0 and starts attacking healthy kidney cells. The disease affects the kidney\u2019s ability to make urine and can cause protein and blood to leak into the urine. Advanced MPGN can lead to kidney failure.\u00a0<\/p>\n\n\n\n<p class=\"hero-p wp-block-paragraph\"><em>Medically reviewed by Dr. Corey Cavanaugh, D.O.<\/em><\/p>\n\n<\/div>\n\n<div class=\"gb-container gb-container-b45e9505\">\n<div class=\"gb-grid-wrapper gb-grid-wrapper-d4ac8e2d\">\n<div class=\"gb-grid-column gb-grid-column-0dc6618f\"><div class=\"gb-container gb-container-0dc6618f\"><\/div><\/div>\n\n<div class=\"gb-grid-column gb-grid-column-ab8ac5ed\"><div class=\"gb-container gb-container-ab8ac5ed\">\n\n<h3 class=\"gb-headline gb-headline-8b25774b gb-headline-text\">Who Gets MPGN<\/h3>\n\n\n\n<p class=\"wp-block-paragraph\">People of all ages can develop MPGN.&nbsp;Most instances of MPGN are caused by other diseases and disorders, including:<\/p>\n\n\n\n<ul class=\"wp-block-list\">\n<li>Autoimmune diseases such as systemic lupus erythematosus<\/li>\n\n\n\n<li>Chronic infections such as hepatitis B or hepatitis C<\/li>\n\n\n\n<li>Hereditary disorders&nbsp;&nbsp;<\/li>\n\n\n\n<li>Monoclonal immunoglobin deposition diseases<\/li>\n<\/ul>\n\n\n\n<p class=\"wp-block-paragraph\">The cause of MPGN cannot be identified in rare instances. This type of MPGN is called primary or idiopathic MPGN, is very rare. It affects about one to two people per million. Primary MPGN is most common in younger people ages 8 to 30.&nbsp;<\/p>\n\n<\/div><\/div>\n<\/div>\n<\/div>\n<\/section>\n\n<div class=\"gb-container gb-container-dd508e5c\">\n<div class=\"gb-container gb-container-c563d239\">\n<div class=\"gb-grid-wrapper gb-grid-wrapper-c8a1e95b\">\n<div class=\"gb-grid-column gb-grid-column-cf6e757b\"><div class=\"gb-container gb-container-cf6e757b\">\n\n<figure class=\"gb-block-image gb-block-image-a7066f5f\"><img loading=\"lazy\" decoding=\"async\" width=\"464\" height=\"441\" class=\"gb-image gb-image-a7066f5f\" src=\"https:\/\/nephcure.org\/wp-content\/uploads\/2024\/04\/group-of-people-Website-Image-Size-for-Colored-Circles.png\" alt=\"\" title=\"group of people Website Image Size for Colored Circles\" srcset=\"https:\/\/nephcure.org\/wp-content\/uploads\/2024\/04\/group-of-people-Website-Image-Size-for-Colored-Circles.png 464w, https:\/\/nephcure.org\/wp-content\/uploads\/2024\/04\/group-of-people-Website-Image-Size-for-Colored-Circles-300x285.png 300w, https:\/\/nephcure.org\/wp-content\/uploads\/2024\/04\/group-of-people-Website-Image-Size-for-Colored-Circles-13x12.png 13w\" sizes=\"auto, (max-width: 464px) 100vw, 464px\" \/><\/figure>\n\n<\/div><\/div>\n\n<div class=\"gb-grid-column gb-grid-column-5e455c53\"><div class=\"gb-container gb-container-5e455c53\">\n\n<figure class=\"gb-block-image gb-block-image-45999f79\"><img loading=\"lazy\" decoding=\"async\" width=\"54\" height=\"4\" class=\"gb-image gb-image-45999f79\" src=\"https:\/\/nephcure.org\/wp-content\/uploads\/2023\/11\/heading-line.svg\" alt=\"\" title=\"heading-line\"\/><\/figure>\n\n\n\n<h3 class=\"gb-headline gb-headline-c266dc1b gb-headline-text\">Signs and Symptoms<\/h3>\n\n\n<div class=\"gb-container gb-container-c1e3b0aa\"><\/div>\n\n\n<p class=\"gb-headline gb-headline-fe22edce gb-headline-text\">Not everyone with MPGN has symptoms, especially in the early stages of the disease.&nbsp;<\/p>\n\n\n\n<p class=\"wp-block-paragraph\"><strong>Signs and symptoms of MPGN include:&nbsp;<\/strong><\/p>\n\n\n\n<ul class=\"wp-block-list\">\n<li>Cloudy, dark or foamy urine<\/li>\n\n\n\n<li>Decreased urine volume<\/li>\n\n\n\n<li>Difficulty focusing and staying alert<\/li>\n\n\n\n<li>Fluid build-up (edema) that causes swelling in areas such as the hands, ankles and around the eyes<\/li>\n\n\n\n<li>High blood pressure<\/li>\n<\/ul>\n\n<\/div><\/div>\n<\/div>\n<\/div>\n\n<div class=\"gb-container gb-container-69f54528\">\n<div class=\"gb-grid-wrapper gb-grid-wrapper-f6391388\">\n<div class=\"gb-grid-column gb-grid-column-1b251990\"><div class=\"gb-container gb-container-1b251990\">\n\n<figure class=\"gb-block-image gb-block-image-04215775\"><img loading=\"lazy\" decoding=\"async\" width=\"2000\" height=\"1333\" class=\"gb-image gb-image-04215775\" src=\"https:\/\/nephcure.org\/wp-content\/uploads\/2024\/11\/Portraits_PatientSummit_NephCure_May9_2024-WEB-4-8643-2.jpg\" alt=\"\" title=\"Portraits_PatientSummit_NephCure_May9_2024-WEB-4-8643 (2)\" srcset=\"https:\/\/nephcure.org\/wp-content\/uploads\/2024\/11\/Portraits_PatientSummit_NephCure_May9_2024-WEB-4-8643-2.jpg 2000w, https:\/\/nephcure.org\/wp-content\/uploads\/2024\/11\/Portraits_PatientSummit_NephCure_May9_2024-WEB-4-8643-2-300x200.jpg 300w, https:\/\/nephcure.org\/wp-content\/uploads\/2024\/11\/Portraits_PatientSummit_NephCure_May9_2024-WEB-4-8643-2-1024x682.jpg 1024w, https:\/\/nephcure.org\/wp-content\/uploads\/2024\/11\/Portraits_PatientSummit_NephCure_May9_2024-WEB-4-8643-2-768x512.jpg 768w, https:\/\/nephcure.org\/wp-content\/uploads\/2024\/11\/Portraits_PatientSummit_NephCure_May9_2024-WEB-4-8643-2-1536x1024.jpg 1536w, https:\/\/nephcure.org\/wp-content\/uploads\/2024\/11\/Portraits_PatientSummit_NephCure_May9_2024-WEB-4-8643-2-18x12.jpg 18w, https:\/\/nephcure.org\/wp-content\/uploads\/2024\/11\/Portraits_PatientSummit_NephCure_May9_2024-WEB-4-8643-2-600x400.jpg 600w\" sizes=\"auto, (max-width: 2000px) 100vw, 2000px\" \/><\/figure>\n\n<\/div><\/div>\n\n<div class=\"gb-grid-column gb-grid-column-f6ca6fd4\"><div class=\"gb-container gb-container-f6ca6fd4\">\n\n<figure class=\"gb-block-image gb-block-image-a10aa848\"><img loading=\"lazy\" decoding=\"async\" width=\"54\" height=\"4\" class=\"gb-image gb-image-a10aa848\" src=\"https:\/\/nephcure.org\/wp-content\/uploads\/2023\/11\/heading-line.svg\" alt=\"\" title=\"heading-line\"\/><\/figure>\n\n\n\n<h3 class=\"gb-headline gb-headline-c38aad44 gb-headline-text\">Diagnosing MPGN<\/h3>\n\n\n<div class=\"gb-container gb-container-c1c0889b\"><\/div>\n\n\n<p class=\"gb-headline gb-headline-0ca4ad95 gb-headline-text\">Testing is the first step if your doctor thinks you may have MPGN. Initial testing can include:<\/p>\n\n\n\n<ul class=\"wp-block-list\">\n<li>A glomerular filtration rate (GFR) calculation to estimate your kidney function. You can&nbsp;<a href=\"https:\/\/www.niddk.nih.gov\/health-information\/professionals\/clinical-tools-patient-management\/kidney-disease\/laboratory-evaluation\/estimated-gfr-calculators?dkrd=\/health-information\/professionals\/clinical-tools-patient-management\/kidney-disease\/laboratory-evaluation\/glomerular-filtration-rate-calculators\">calculate your GFR<\/a>&nbsp;if you know your blood creatinine and urine protein levels.<\/li>\n\n\n\n<li>A urine test to reveal the presence of blood or protein in your urine<\/li>\n<\/ul>\n\n\n\n<p class=\"gb-headline gb-headline-fd71034b gb-headline-text\">If test results suggest you may have MPGN, your doctor will order a kidney biopsy. A biopsy is the only way to be sure that you have MPGN. The procedure involves removing a tiny portion of the kidney tissue and testing it in the lab.&nbsp;<br><\/p>\n\n\n\n<p class=\"wp-block-paragraph\">Once your care team confirms the diagnosis of MPGN, your doctor may order additional tests. <strong>The results can help guide treatment and may include:<\/strong><\/p>\n\n\n\n<ul class=\"wp-block-list\">\n<li>Advanced complement system testing<\/li>\n\n\n\n<li>Blood tests to find out whether you have an autoimmune disease or infections<\/li>\n\n\n\n<li>Genetic testing to see if you have an inherited form of MPGN<\/li>\n<\/ul>\n\n<\/div><\/div>\n<\/div>\n<\/div>\n\n<div class=\"gb-container gb-container-e23189e2\">\n<div class=\"gb-grid-wrapper gb-grid-wrapper-fe9d6ccd\">\n<div class=\"gb-grid-column gb-grid-column-84ff3e7e\"><div class=\"gb-container gb-container-84ff3e7e\">\n\n<figure class=\"gb-block-image gb-block-image-e8e4a274\"><img loading=\"lazy\" decoding=\"async\" width=\"2000\" height=\"1333\" class=\"gb-image gb-image-e8e4a274\" src=\"https:\/\/nephcure.org\/wp-content\/uploads\/2024\/04\/Portraits_PatientSummit_NephCure_May9_2024-WEB-7-8690.jpg\" alt=\"\" title=\"Portraits_PatientSummit_NephCure_May9_2024-WEB-7-8690\" srcset=\"https:\/\/nephcure.org\/wp-content\/uploads\/2024\/04\/Portraits_PatientSummit_NephCure_May9_2024-WEB-7-8690.jpg 2000w, https:\/\/nephcure.org\/wp-content\/uploads\/2024\/04\/Portraits_PatientSummit_NephCure_May9_2024-WEB-7-8690-300x200.jpg 300w, https:\/\/nephcure.org\/wp-content\/uploads\/2024\/04\/Portraits_PatientSummit_NephCure_May9_2024-WEB-7-8690-1024x682.jpg 1024w, https:\/\/nephcure.org\/wp-content\/uploads\/2024\/04\/Portraits_PatientSummit_NephCure_May9_2024-WEB-7-8690-768x512.jpg 768w, https:\/\/nephcure.org\/wp-content\/uploads\/2024\/04\/Portraits_PatientSummit_NephCure_May9_2024-WEB-7-8690-1536x1024.jpg 1536w, https:\/\/nephcure.org\/wp-content\/uploads\/2024\/04\/Portraits_PatientSummit_NephCure_May9_2024-WEB-7-8690-18x12.jpg 18w, https:\/\/nephcure.org\/wp-content\/uploads\/2024\/04\/Portraits_PatientSummit_NephCure_May9_2024-WEB-7-8690-600x400.jpg 600w\" sizes=\"auto, (max-width: 2000px) 100vw, 2000px\" \/><\/figure>\n\n<\/div><\/div>\n\n<div class=\"gb-grid-column gb-grid-column-eb1086dc\"><div class=\"gb-container gb-container-eb1086dc\">\n\n<figure class=\"gb-block-image gb-block-image-cb51b2f9\"><img loading=\"lazy\" decoding=\"async\" width=\"54\" height=\"4\" class=\"gb-image gb-image-cb51b2f9\" src=\"https:\/\/nephcure.org\/wp-content\/uploads\/2023\/11\/heading-line.svg\" alt=\"\" title=\"heading-line\"\/><\/figure>\n\n\n\n<h3 class=\"gb-headline gb-headline-076180d2 gb-headline-text\">Your Treatment Options<\/h3>\n\n\n<div class=\"gb-container gb-container-d587de1e\"><\/div>\n\n\n<p class=\"wp-block-paragraph\">Treatment depends on the underlying cause of MPGN. When caused by another condition, MPGN usually goes away if the other disease responds well to treatment.&nbsp;<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">There is no cure for primary MPGN. Treatment focuses on slowing the kidney damage. Your doctor may prescribe several therapies to help manage your symptoms.&nbsp;<\/p>\n\n\n\n<ul class=\"wp-block-list\">\n<li>Corticosteroids and other medicines, such as mycophenolate mofetil and rituximab, to help reduce your immune system response<\/li>\n\n\n\n<li>Medicines such as ACE inhibitors (angiotensin-converting enzymes) and ARB (angiotensin receptor blockers) can reduce protein loss and help manage your blood pressure<\/li>\n\n\n\n<li>Participation in a clinical trial<\/li>\n<\/ul>\n\n<\/div><\/div>\n<\/div>\n<\/div>\n<\/div>\n\n<div class=\"gb-container gb-container-c7966d90\">\n<div class=\"gb-container gb-container-4d8a4fe1\">\n\n<figure class=\"gb-block-image gb-block-image-9ab43e4d\"><img loading=\"lazy\" decoding=\"async\" width=\"54\" height=\"4\" class=\"gb-image gb-image-9ab43e4d\" src=\"https:\/\/nephcure.org\/wp-content\/uploads\/2023\/11\/heading-line.svg\" alt=\"Headline decoration line\" title=\"heading-line\"\/><\/figure>\n\n\n\n<h2 class=\"gb-headline gb-headline-afffeb92 gb-headline-text\">Clinical trials are another treatment option.<\/h2>\n\n\n\n<p class=\"gb-headline gb-headline-14d28465 gb-headline-text\">Your doctor helps you find the right study for you. These trials test more targeted treatments with potentially lower risks of side effects.<br><br>Some clinical trials enroll patients, based on their genetic testing results, to test the effectiveness of precision-based therapies targeted to specific genetic changes.<\/p>\n\n\n\n<a class=\"gb-button gb-button-52ab81c1 gb-button-text gb-button-primary button\" href=\"https:\/\/nephcure.org\/managing-rkd\/clinical-trials\/\">Explore<\/a>\n\n<\/div>\n\n\n<figure class=\"gb-block-image gb-block-image-5eb3ff4b\"><img loading=\"lazy\" decoding=\"async\" width=\"584\" height=\"583\" class=\"gb-image gb-image-5eb3ff4b\" src=\"https:\/\/nephcure.org\/wp-content\/uploads\/2023\/12\/illustration.png\" alt=\"\" title=\"illustration\" srcset=\"https:\/\/nephcure.org\/wp-content\/uploads\/2023\/12\/illustration.png 584w, https:\/\/nephcure.org\/wp-content\/uploads\/2023\/12\/illustration-300x300.png 300w, https:\/\/nephcure.org\/wp-content\/uploads\/2023\/12\/illustration-150x150.png 150w\" sizes=\"auto, (max-width: 584px) 100vw, 584px\" \/><\/figure>\n\n<\/div>\n\n<div class=\"gb-container gb-container-5dba5269\">\n\n<figure class=\"gb-block-image gb-block-image-63925bfe\"><img loading=\"lazy\" decoding=\"async\" width=\"54\" height=\"4\" class=\"gb-image gb-image-63925bfe\" src=\"https:\/\/nephcure.org\/wp-content\/uploads\/2023\/11\/heading-line.svg\" alt=\"\" title=\"heading-line\"\/><\/figure>\n\n\n\n<h2 class=\"gb-headline gb-headline-6144db93 gb-headline-text\">Tips For Living With MPGN<\/h2>\n\n\n\n<p class=\"gb-headline gb-headline-a2abe2fd gb-headline-text\">Your care team can help you manage your condition.<\/p>\n\n\n<div class=\"gb-container gb-container-44b42b9e\">\n<div class=\"gb-grid-wrapper gb-grid-wrapper-f5f75bf0\">\n<div class=\"gb-grid-column gb-grid-column-e37c2bbf\"><div class=\"gb-container gb-container-e37c2bbf\">\n<div class=\"gb-container gb-container-bc0ff6c3\">\n\n<h4 class=\"gb-headline gb-headline-d237c6e7 gb-headline-text\"><strong>Prevent Infections<\/strong><\/h4>\n\n\n\n<p class=\"gb-headline gb-headline-94cc70f1 gb-headline-text\">Your doctor can help you learn how to lower your risk and recognize early signs of an infection.&nbsp;<\/p>\n\n<\/div>\n<\/div><\/div>\n\n<div class=\"gb-grid-column gb-grid-column-1c7441e8\"><div class=\"gb-container gb-container-1c7441e8\">\n<div class=\"gb-container gb-container-ac344a59\">\n\n<h4 class=\"gb-headline gb-headline-136bf5ec gb-headline-text\"><strong>Medicine<\/strong><\/h4>\n\n\n\n<p class=\"gb-headline gb-headline-df79a8f4 gb-headline-text\">Follow your doctor\u2019s instructions and take your medicines as prescribed.<\/p>\n\n<\/div>\n<\/div><\/div>\n\n<div class=\"gb-grid-column gb-grid-column-4c659ea0\"><div class=\"gb-container gb-container-4c659ea0\">\n<div class=\"gb-container gb-container-cb224451\">\n\n<h4 class=\"gb-headline gb-headline-ab6868a1 gb-headline-text\"><strong>Work With Your Care Team<\/strong><\/h4>\n\n\n\n<p class=\"gb-headline gb-headline-c62e9f89 gb-headline-text\">See your nephrologist routinely for tests and to learn more about how to manage your health.<\/p>\n\n<\/div>\n<\/div><\/div>\n<\/div>\n<\/div>\n<\/div>\n\n<div class=\"gb-container gb-container-a7f6f996 gb-container-default\">\n\n<figure class=\"gb-block-image gb-block-image-594a969c\"><img loading=\"lazy\" decoding=\"async\" width=\"54\" height=\"4\" class=\"gb-image gb-image-594a969c\" src=\"https:\/\/nephcure.org\/wp-content\/uploads\/2023\/11\/heading-line.svg\" alt=\"\" title=\"heading-line\"\/><\/figure>\n\n\n\n<h2 class=\"gb-headline gb-headline-2c8c340e gb-headline-text\">Your Nephrologist May Also Recommend<\/h2>\n\n\n<div class=\"gb-grid-wrapper gb-grid-wrapper-d20d7806\">\n<div class=\"gb-grid-column gb-grid-column-b4821127\"><div class=\"gb-container gb-container-b4821127\">\n<div class=\"gb-container gb-container-0c1e34f4\">\n\n<p class=\"gb-headline gb-headline-fefd642f gb-headline-text\">1<\/p>\n\n<\/div>\n\n<div class=\"gb-container gb-container-0d793e34\">\n\n<h4 class=\"gb-headline gb-headline-40187694 gb-headline-text\">Diuretics<\/h4>\n\n\n\n<p class=\"gb-headline gb-headline-3a752d97 gb-headline-text\">Diuretics help manage fluid retention and edema, common complications of MPGN.<\/p>\n\n<\/div>\n<\/div><\/div>\n\n<div class=\"gb-grid-column gb-grid-column-bed04ea1\"><div class=\"gb-container gb-container-bed04ea1\">\n<div class=\"gb-container gb-container-b12e457e\">\n\n<p class=\"gb-headline gb-headline-a531aac6 gb-headline-text\">2<\/p>\n\n<\/div>\n\n<div class=\"gb-container gb-container-5a630bd2\">\n\n<h4 class=\"gb-headline gb-headline-8973b35c gb-headline-text\">Anticoagulants<\/h4>\n\n\n\n<p class=\"gb-headline gb-headline-2de340ff gb-headline-text\">Anticoagulants are essential for people with rare kidney diseases. They prevent the formation of blood clots.<\/p>\n\n<\/div>\n<\/div><\/div>\n\n<div class=\"gb-grid-column gb-grid-column-0ddf87e3\"><div class=\"gb-container gb-container-0ddf87e3\">\n<div class=\"gb-container gb-container-f666a0aa\">\n\n<p class=\"gb-headline gb-headline-9b29460d gb-headline-text\">3<\/p>\n\n<\/div>\n\n<div class=\"gb-container gb-container-0ff287bb\">\n\n<h4 class=\"gb-headline gb-headline-443a7779 gb-headline-text\">Medications<\/h4>\n\n\n\n<p class=\"gb-headline gb-headline-897d42f2 gb-headline-text\">Blood pressure medicines help lower your blood pressure. Statin medicines can reduce your cholesterol level.<\/p>\n\n<\/div>\n<\/div><\/div>\n\n<div class=\"gb-grid-column gb-grid-column-3e5d0248\"><div class=\"gb-container gb-container-3e5d0248\">\n<div class=\"gb-container gb-container-f766c2fb\">\n\n<p class=\"gb-headline gb-headline-1f63c1ec gb-headline-text\">4<\/p>\n\n<\/div>\n\n<div class=\"gb-container gb-container-cb048190\">\n\n<h4 class=\"gb-headline gb-headline-e827a588 gb-headline-text\">Vitamins<\/h4>\n\n\n\n<p class=\"gb-headline gb-headline-f60b0f48 gb-headline-text\">Vitamins are crucial in supporting overall health and lowering the risk of complications.<\/p>\n\n<\/div>\n<\/div><\/div>\n<\/div>\n<\/div>\n\n<div class=\"gb-container gb-container-3dd326cd gb-container-default\">\n\n<figure class=\"gb-block-image gb-block-image-f04b9551\"><img loading=\"lazy\" decoding=\"async\" width=\"54\" height=\"4\" class=\"gb-image gb-image-f04b9551\" src=\"https:\/\/nephcure.org\/wp-content\/uploads\/2023\/11\/heading-line.svg\" alt=\"\" title=\"heading-line\"\/><\/figure>\n\n\n\n<h2 class=\"gb-headline gb-headline-a237975b gb-headline-text\">Kidney Transplant and MPGN<\/h2>\n\n\n\n<p class=\"has-text-align-center wp-block-paragraph\">Kidney transplantation is an option for people who develop kidney failure due to MPGN. After the transplant, doctors use a transplant kidney biopsy to check whether the disease has returned. About 15% of people with MPGN develop recurrent MPGN within five years of their transplant.&nbsp;<\/p>\n\n<\/div>\n\n<div class=\"gb-container gb-container-1cc9a3b0\">\n<div class=\"gb-grid-wrapper gb-grid-wrapper-f678360f\">\n<div class=\"gb-grid-column gb-grid-column-faba6f4c\"><div class=\"gb-container gb-container-faba6f4c\">\n<div class=\"gb-container gb-container-58595147\">\n\n<h2 class=\"gb-headline gb-headline-706921bd gb-headline-text\">Support<\/h2>\n\n\n\n<p class=\"gb-headline gb-headline-b0f6772e gb-headline-text\">Get help coping with the challenges of living with MPGN through support groups. Connect with others who understand your journey, share experiences, and find comfort in knowing you\u2019re not alone.<\/p>\n\n<\/div>\n\n<div class=\"gb-container gb-container-5fe04f4b\"><a class=\"gb-container-link\" href=\"https:\/\/nephcure.org\/support\/\"><\/a>\n\n<p class=\"gb-headline gb-headline-1225e0b4\"><span class=\"gb-icon\"><svg fill=\"none\" viewBox=\"0 0 27 24\" height=\"24\" width=\"27\" xmlns=\"http:\/\/www.w3.org\/2000\/svg\"> <path fill=\"#00556B\" d=\"M26.0607 13.0607C26.6464 12.4749 26.6464 11.5251 26.0607 10.9393L16.5147 1.3934C15.9289 0.807611 14.9792 0.807611 14.3934 1.3934C13.8076 1.97919 13.8076 2.92893 14.3934 3.51472L22.8787 12L14.3934 20.4853C13.8076 21.0711 13.8076 22.0208 14.3934 22.6066C14.9792 23.1924 15.9289 23.1924 16.5147 22.6066L26.0607 13.0607ZM0 13.5H25V10.5H0V13.5Z\"><\/path> <\/svg><\/span><\/p>\n\n<\/div>\n<\/div><\/div>\n\n<div class=\"gb-grid-column gb-grid-column-6ce89e03\"><div class=\"gb-container gb-container-6ce89e03\">\n<div class=\"gb-container gb-container-355b5591\">\n\n<h2 class=\"gb-headline gb-headline-6f8b3340 gb-headline-text\">Nutrition<\/h2>\n\n\n\n<p class=\"gb-headline gb-headline-f52fd292 gb-headline-text\">Eating a kidney-friendly diet can help manage the symptoms and progression of your RKD. Learn more about a kidney-friendly diet and get our cookbook.<\/p>\n\n<\/div>\n\n<div class=\"gb-container gb-container-22cf50d4\"><a class=\"gb-container-link\" href=\"https:\/\/nephcure.org\/managing-rkd\/diet-and-nutrition\/\"><\/a>\n\n<p class=\"gb-headline gb-headline-3a61379c\"><span class=\"gb-icon\"><svg fill=\"none\" viewBox=\"0 0 27 24\" height=\"24\" width=\"27\" xmlns=\"http:\/\/www.w3.org\/2000\/svg\"> <path fill=\"#00556B\" d=\"M26.0607 13.0607C26.6464 12.4749 26.6464 11.5251 26.0607 10.9393L16.5147 1.3934C15.9289 0.807611 14.9792 0.807611 14.3934 1.3934C13.8076 1.97919 13.8076 2.92893 14.3934 3.51472L22.8787 12L14.3934 20.4853C13.8076 21.0711 13.8076 22.0208 14.3934 22.6066C14.9792 23.1924 15.9289 23.1924 16.5147 22.6066L26.0607 13.0607ZM0 13.5H25V10.5H0V13.5Z\"><\/path> <\/svg><\/span><\/p>\n\n<\/div>\n<\/div><\/div>\n<\/div>\n<\/div>\n\n<div class=\"gb-container gb-container-5f18cf75\">\n<div class=\"gb-container gb-container-0018102f\">\n\n<figure class=\"gb-block-image gb-block-image-40625f55\"><img loading=\"lazy\" decoding=\"async\" width=\"54\" height=\"4\" class=\"gb-image gb-image-40625f55\" src=\"https:\/\/kidneydevelop.wpengine.com\/wp-content\/uploads\/2023\/11\/heading-line.svg\" alt=\"\" title=\"heading-line\"\/><\/figure>\n\n\n\n<h2 class=\"gb-headline gb-headline-33d24afb gb-headline-text\">Related Resources<\/h2>\n\n\n<div class=\"gb-container gb-container-8a0bd972\">\n\n<div class=\"gb-grid-wrapper gb-grid-wrapper-2bf95862 resource-cards-loop  gb-query-loop-wrapper\" data-posts=\"post\">\n<div class=\"gb-grid-column gb-grid-column-32674dd1 gb-query-loop-item post-38008 post type-post status-publish format-standard has-post-thumbnail hentry category-uncategorized disease-category-focal-segmental-glomerulosclerosis-fsgs resource-type-informational-documents\"><div class=\"gb-container gb-container-32674dd1 resource-loop-card\">\n<div class=\"gb-container gb-container-6abd4867 recourses-grid-card\"><a class=\"gb-container-link\" href=\"https:\/\/nephcure.org\/es\/sparsentan-filspari-for-fsgs-faqs\/\"><\/a>\n<div class=\"gb-container gb-container-98d50fd4 resource-terms-play post-card-thumbnail\">\n<figure class=\"gb-block-image gb-block-image-ca750b16\"><img loading=\"lazy\" decoding=\"async\" width=\"1200\" height=\"675\" src=\"https:\/\/nephcure.org\/wp-content\/uploads\/2024\/05\/Site-Image.jpg\" class=\"gb-image-ca750b16\" alt=\"Nephcure Site Image\" srcset=\"https:\/\/nephcure.org\/wp-content\/uploads\/2024\/05\/Site-Image.jpg 1200w, https:\/\/nephcure.org\/wp-content\/uploads\/2024\/05\/Site-Image-300x169.jpg 300w, https:\/\/nephcure.org\/wp-content\/uploads\/2024\/05\/Site-Image-1024x576.jpg 1024w, https:\/\/nephcure.org\/wp-content\/uploads\/2024\/05\/Site-Image-768x432.jpg 768w, https:\/\/nephcure.org\/wp-content\/uploads\/2024\/05\/Site-Image-18x10.jpg 18w\" sizes=\"auto, (max-width: 1200px) 100vw, 1200px\" \/><\/figure>\n\n<div class=\"gb-container gb-container-55e46ef5 video-btn\">\n\n<svg xmlns=\"http:\/\/www.w3.org\/2000\/svg\" width=\"149\" height=\"149\" viewBox=\"0 0 149 149\" fill=\"none\">\n  <g filter=\"url(#filter0_d_172_269)\">\n    <circle cx=\"74.5\" cy=\"62.5\" r=\"62.5\" fill=\"#F2F2F2\"\/>\n    <path class = \"resource-svg-icon\" d=\"M97.6826 60.7681C99.0159 61.5379 99.0159 63.4624 97.6826 64.2322L64.409 83.4428C63.0756 84.2126 61.409 83.2503 61.409 81.7107L61.409 43.2896C61.409 41.75 63.0756 40.7878 64.409 41.5576L97.6826 60.7681Z\" fill=\"#3AC2BA\"\/>\n  <\/g>\n  <defs>\n    <filter id=\"filter0_d_172_269\" x=\"0\" y=\"0\" width=\"149\" height=\"149\" filterUnits=\"userSpaceOnUse\" color-interpolation-filters=\"sRGB\">\n      <feFlood flood-opacity=\"0\" result=\"BackgroundImageFix\"\/>\n      <feColorMatrix in=\"SourceAlpha\" type=\"matrix\" values=\"0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 127 0\" result=\"hardAlpha\"\/>\n      <feOffset dy=\"12\"\/>\n      <feGaussianBlur stdDeviation=\"6\"\/>\n      <feComposite in2=\"hardAlpha\" operator=\"out\"\/>\n      <feColorMatrix type=\"matrix\" values=\"0 0 0 0 0.00364583 0 0 0 0 0.232447 0 0 0 0 0.291667 0 0 0 0.2 0\"\/>\n      <feBlend mode=\"normal\" in2=\"BackgroundImageFix\" result=\"effect1_dropShadow_172_269\"\/>\n      <feBlend mode=\"normal\" in=\"SourceGraphic\" in2=\"effect1_dropShadow_172_269\" result=\"shape\"\/>\n    <\/filter>\n  <\/defs>\n<\/svg>\n\n<\/div>\n<\/div><style>.post-38008 .recourses-grid-card .video-btn { display : none } <\/style>\n\n<span style=\"color: #c2005d !important;\" class=\"resource-terms-label\">Informational Documents<\/span>\n\n<h4 class=\"gb-headline gb-headline-e0f58ce0 gb-headline-text\">Sparsentan\u00a0(FILSPARI) for FSGS:\u00a0FAQs<\/h4>\n<\/div>\n<\/div><\/div>\n\n<div class=\"gb-grid-column gb-grid-column-32674dd1 gb-query-loop-item post-27575 post type-post status-publish format-standard has-post-thumbnail hentry category-printable-resource tag-cns tag-ins tag-rare-kidney-disease tag-support disease-category-congenital-infantile-nephrotic-syndrome-cns-ins resource-type-fact-sheet\"><div class=\"gb-container gb-container-32674dd1 resource-loop-card\">\n<div class=\"gb-container gb-container-6abd4867 recourses-grid-card\"><a class=\"gb-container-link\" href=\"https:\/\/nephcure.org\/es\/congenital-nephrotic-syndrome-infantile-nephrotic-syndrome\/\"><\/a>\n<div class=\"gb-container gb-container-98d50fd4 resource-terms-play post-card-thumbnail\">\n<figure class=\"gb-block-image gb-block-image-ca750b16\"><img loading=\"lazy\" decoding=\"async\" width=\"340\" height=\"211\" src=\"https:\/\/nephcure.org\/wp-content\/uploads\/2024\/04\/CNSINS.png\" class=\"gb-image-ca750b16\" alt=\"\" srcset=\"https:\/\/nephcure.org\/wp-content\/uploads\/2024\/04\/CNSINS.png 340w, https:\/\/nephcure.org\/wp-content\/uploads\/2024\/04\/CNSINS-300x186.png 300w, https:\/\/nephcure.org\/wp-content\/uploads\/2024\/04\/CNSINS-18x12.png 18w\" sizes=\"auto, (max-width: 340px) 100vw, 340px\" \/><\/figure>\n\n<div class=\"gb-container gb-container-55e46ef5 video-btn\">\n\n<svg xmlns=\"http:\/\/www.w3.org\/2000\/svg\" width=\"149\" height=\"149\" viewBox=\"0 0 149 149\" fill=\"none\">\n  <g filter=\"url(#filter0_d_172_269)\">\n    <circle cx=\"74.5\" cy=\"62.5\" r=\"62.5\" fill=\"#F2F2F2\"\/>\n    <path class = \"resource-svg-icon\" d=\"M97.6826 60.7681C99.0159 61.5379 99.0159 63.4624 97.6826 64.2322L64.409 83.4428C63.0756 84.2126 61.409 83.2503 61.409 81.7107L61.409 43.2896C61.409 41.75 63.0756 40.7878 64.409 41.5576L97.6826 60.7681Z\" fill=\"#3AC2BA\"\/>\n  <\/g>\n  <defs>\n    <filter id=\"filter0_d_172_269\" x=\"0\" y=\"0\" width=\"149\" height=\"149\" filterUnits=\"userSpaceOnUse\" color-interpolation-filters=\"sRGB\">\n      <feFlood flood-opacity=\"0\" result=\"BackgroundImageFix\"\/>\n      <feColorMatrix in=\"SourceAlpha\" type=\"matrix\" values=\"0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 127 0\" result=\"hardAlpha\"\/>\n      <feOffset dy=\"12\"\/>\n      <feGaussianBlur stdDeviation=\"6\"\/>\n      <feComposite in2=\"hardAlpha\" operator=\"out\"\/>\n      <feColorMatrix type=\"matrix\" values=\"0 0 0 0 0.00364583 0 0 0 0 0.232447 0 0 0 0 0.291667 0 0 0 0.2 0\"\/>\n      <feBlend mode=\"normal\" in2=\"BackgroundImageFix\" result=\"effect1_dropShadow_172_269\"\/>\n      <feBlend mode=\"normal\" in=\"SourceGraphic\" in2=\"effect1_dropShadow_172_269\" result=\"shape\"\/>\n    <\/filter>\n  <\/defs>\n<\/svg>\n\n<\/div>\n<\/div><style>.post-27575 .recourses-grid-card .video-btn { display : none } <\/style>\n\n<span style=\"color: #951f97 !important;\" class=\"resource-terms-label\">Fact Sheet<\/span>\n\n<h4 class=\"gb-headline gb-headline-e0f58ce0 gb-headline-text\">Congenital Nephrotic Syndrome &amp; Infantile Nephrotic Syndrome<\/h4>\n<\/div>\n<\/div><\/div>\n\n<div class=\"gb-grid-column gb-grid-column-32674dd1 gb-query-loop-item post-38012 post type-post status-publish format-standard has-post-thumbnail hentry category-video tag-fsgs tag-video resource-type-video\"><div class=\"gb-container gb-container-32674dd1 resource-loop-card\">\n<div class=\"gb-container gb-container-6abd4867 recourses-grid-card\"><a class=\"gb-container-link\" href=\"https:\/\/nephcure.org\/es\/a-first-for-fsgs-patients-what-the-sparsentan-approval-means-for-you\/\"><\/a>\n<div class=\"gb-container gb-container-98d50fd4 resource-terms-play post-card-thumbnail\">\n<figure class=\"gb-block-image gb-block-image-ca750b16\"><img loading=\"lazy\" decoding=\"async\" width=\"2212\" height=\"1126\" src=\"https:\/\/nephcure.org\/wp-content\/uploads\/2026\/04\/a-first-for-fsgs-patients-sparsentan-approval.png\" class=\"gb-image-ca750b16\" alt=\"\" srcset=\"https:\/\/nephcure.org\/wp-content\/uploads\/2026\/04\/a-first-for-fsgs-patients-sparsentan-approval.png 2212w, https:\/\/nephcure.org\/wp-content\/uploads\/2026\/04\/a-first-for-fsgs-patients-sparsentan-approval-300x153.png 300w, https:\/\/nephcure.org\/wp-content\/uploads\/2026\/04\/a-first-for-fsgs-patients-sparsentan-approval-1024x521.png 1024w, https:\/\/nephcure.org\/wp-content\/uploads\/2026\/04\/a-first-for-fsgs-patients-sparsentan-approval-768x391.png 768w, https:\/\/nephcure.org\/wp-content\/uploads\/2026\/04\/a-first-for-fsgs-patients-sparsentan-approval-1536x782.png 1536w, https:\/\/nephcure.org\/wp-content\/uploads\/2026\/04\/a-first-for-fsgs-patients-sparsentan-approval-2048x1043.png 2048w, https:\/\/nephcure.org\/wp-content\/uploads\/2026\/04\/a-first-for-fsgs-patients-sparsentan-approval-18x9.png 18w, https:\/\/nephcure.org\/wp-content\/uploads\/2026\/04\/a-first-for-fsgs-patients-sparsentan-approval-600x305.png 600w\" sizes=\"auto, (max-width: 2212px) 100vw, 2212px\" \/><\/figure>\n\n<div class=\"gb-container gb-container-55e46ef5 video-btn\">\n\n<svg xmlns=\"http:\/\/www.w3.org\/2000\/svg\" width=\"149\" height=\"149\" viewBox=\"0 0 149 149\" fill=\"none\">\n  <g filter=\"url(#filter0_d_172_269)\">\n    <circle cx=\"74.5\" cy=\"62.5\" r=\"62.5\" fill=\"#F2F2F2\"\/>\n    <path class = \"resource-svg-icon\" d=\"M97.6826 60.7681C99.0159 61.5379 99.0159 63.4624 97.6826 64.2322L64.409 83.4428C63.0756 84.2126 61.409 83.2503 61.409 81.7107L61.409 43.2896C61.409 41.75 63.0756 40.7878 64.409 41.5576L97.6826 60.7681Z\" fill=\"#3AC2BA\"\/>\n  <\/g>\n  <defs>\n    <filter id=\"filter0_d_172_269\" x=\"0\" y=\"0\" width=\"149\" height=\"149\" filterUnits=\"userSpaceOnUse\" color-interpolation-filters=\"sRGB\">\n      <feFlood flood-opacity=\"0\" result=\"BackgroundImageFix\"\/>\n      <feColorMatrix in=\"SourceAlpha\" type=\"matrix\" values=\"0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 127 0\" result=\"hardAlpha\"\/>\n      <feOffset dy=\"12\"\/>\n      <feGaussianBlur stdDeviation=\"6\"\/>\n      <feComposite in2=\"hardAlpha\" operator=\"out\"\/>\n      <feColorMatrix type=\"matrix\" values=\"0 0 0 0 0.00364583 0 0 0 0 0.232447 0 0 0 0 0.291667 0 0 0 0.2 0\"\/>\n      <feBlend mode=\"normal\" in2=\"BackgroundImageFix\" result=\"effect1_dropShadow_172_269\"\/>\n      <feBlend mode=\"normal\" in=\"SourceGraphic\" in2=\"effect1_dropShadow_172_269\" result=\"shape\"\/>\n    <\/filter>\n  <\/defs>\n<\/svg>\n\n<\/div>\n<\/div><style>.post-38012 .recourses-grid-card .video-btn path { fill : #3ac2ba } <\/style>\n\n<span style=\"color: #3ac2ba !important;\" class=\"resource-terms-label\">Video<\/span>\n\n<h4 class=\"gb-headline gb-headline-e0f58ce0 gb-headline-text\">A First for FSGS Patients: What the sparsentan Approval Means for You<\/h4>\n<\/div>\n<\/div><\/div>\n\n<div class=\"gb-grid-column gb-grid-column-32674dd1 gb-query-loop-item post-28407 post type-post status-publish format-standard has-post-thumbnail hentry category-printable-resource tag-children tag-navigating-school tag-parents resource-type-educational-materials\"><div class=\"gb-container gb-container-32674dd1 resource-loop-card\">\n<div class=\"gb-container gb-container-6abd4867 recourses-grid-card\"><a class=\"gb-container-link\" href=\"https:\/\/nephcure.org\/es\/school-accomodations\/\"><\/a>\n<div class=\"gb-container gb-container-98d50fd4 resource-terms-play post-card-thumbnail\">\n<figure class=\"gb-block-image gb-block-image-ca750b16\"><img loading=\"lazy\" decoding=\"async\" width=\"2560\" height=\"1709\" src=\"https:\/\/nephcure.org\/wp-content\/uploads\/2024\/04\/pexels-pavel-danilyuk-8763034-scaled.jpg\" class=\"gb-image-ca750b16\" alt=\"\" srcset=\"https:\/\/nephcure.org\/wp-content\/uploads\/2024\/04\/pexels-pavel-danilyuk-8763034-scaled.jpg 2560w, https:\/\/nephcure.org\/wp-content\/uploads\/2024\/04\/pexels-pavel-danilyuk-8763034-300x200.jpg 300w, https:\/\/nephcure.org\/wp-content\/uploads\/2024\/04\/pexels-pavel-danilyuk-8763034-1024x684.jpg 1024w, https:\/\/nephcure.org\/wp-content\/uploads\/2024\/04\/pexels-pavel-danilyuk-8763034-768x513.jpg 768w, https:\/\/nephcure.org\/wp-content\/uploads\/2024\/04\/pexels-pavel-danilyuk-8763034-1536x1025.jpg 1536w, https:\/\/nephcure.org\/wp-content\/uploads\/2024\/04\/pexels-pavel-danilyuk-8763034-2048x1367.jpg 2048w, https:\/\/nephcure.org\/wp-content\/uploads\/2024\/04\/pexels-pavel-danilyuk-8763034-18x12.jpg 18w\" sizes=\"auto, (max-width: 2560px) 100vw, 2560px\" \/><\/figure>\n\n<div class=\"gb-container gb-container-55e46ef5 video-btn\">\n\n<svg xmlns=\"http:\/\/www.w3.org\/2000\/svg\" width=\"149\" height=\"149\" viewBox=\"0 0 149 149\" fill=\"none\">\n  <g filter=\"url(#filter0_d_172_269)\">\n    <circle cx=\"74.5\" cy=\"62.5\" r=\"62.5\" fill=\"#F2F2F2\"\/>\n    <path class = \"resource-svg-icon\" d=\"M97.6826 60.7681C99.0159 61.5379 99.0159 63.4624 97.6826 64.2322L64.409 83.4428C63.0756 84.2126 61.409 83.2503 61.409 81.7107L61.409 43.2896C61.409 41.75 63.0756 40.7878 64.409 41.5576L97.6826 60.7681Z\" fill=\"#3AC2BA\"\/>\n  <\/g>\n  <defs>\n    <filter id=\"filter0_d_172_269\" x=\"0\" y=\"0\" width=\"149\" height=\"149\" filterUnits=\"userSpaceOnUse\" color-interpolation-filters=\"sRGB\">\n      <feFlood flood-opacity=\"0\" result=\"BackgroundImageFix\"\/>\n      <feColorMatrix in=\"SourceAlpha\" type=\"matrix\" values=\"0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 127 0\" result=\"hardAlpha\"\/>\n      <feOffset dy=\"12\"\/>\n      <feGaussianBlur stdDeviation=\"6\"\/>\n      <feComposite in2=\"hardAlpha\" operator=\"out\"\/>\n      <feColorMatrix type=\"matrix\" values=\"0 0 0 0 0.00364583 0 0 0 0 0.232447 0 0 0 0 0.291667 0 0 0 0.2 0\"\/>\n      <feBlend mode=\"normal\" in2=\"BackgroundImageFix\" result=\"effect1_dropShadow_172_269\"\/>\n      <feBlend mode=\"normal\" in=\"SourceGraphic\" in2=\"effect1_dropShadow_172_269\" result=\"shape\"\/>\n    <\/filter>\n  <\/defs>\n<\/svg>\n\n<\/div>\n<\/div><style>.post-28407 .recourses-grid-card .video-btn { display : none } <\/style>\n\n<span style=\"color: #3456e8 !important;\" class=\"resource-terms-label\">Educational Materials<\/span>\n\n<h4 class=\"gb-headline gb-headline-e0f58ce0 gb-headline-text\">School Accomodations<\/h4>\n<\/div>\n<\/div><\/div>\n<\/div>\n\n<\/div>\n\n\n<a class=\"gb-button gb-button-00ad366d gb-button-text gb-button-primary button\" href=\"\/resources\/\">ALL RESOURCES<\/a>\n\n<\/div>\n\n<div class=\"gb-container gb-container-42105b23 news-letter-sec alignfull\">\n\n<figure class=\"gb-block-image gb-block-image-b3f3ccb8\"><img loading=\"lazy\" decoding=\"async\" width=\"1920\" height=\"120\" class=\"gb-image gb-image-b3f3ccb8\" src=\"https:\/\/nephcure.org\/wp-content\/uploads\/2023\/11\/purple-curve.svg\" alt=\"\" title=\"purple-curve\"\/><\/figure>\n\n\n<div class=\"gb-container gb-container-41717e70 alignwide\">\n\n<h2 class=\"gb-headline gb-headline-1760ac29 gb-headline-text\">Sign up to get NephCure\u2019s latest updates.<\/h2>\n\n\n\n<a class=\"gb-button gb-button-753f318a gb-button-text gb-button-primary button\" href=\"\/newsletter\/\">SIGN UP<\/a>\n\n\n<div 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