{"id":28693,"date":"2024-04-12T16:18:34","date_gmt":"2024-04-12T20:18:34","guid":{"rendered":"https:\/\/nephcure.org\/?page_id=28693"},"modified":"2026-02-23T12:22:47","modified_gmt":"2026-02-23T17:22:47","slug":"nefropatia-membranosa-mn","status":"publish","type":"page","link":"https:\/\/nephcure.org\/es\/intro-to-rkd\/types-of-rkd\/membranous-nephropathy-mn\/","title":{"rendered":"Nefropat\u00eda membranosa (MN)"},"content":{"rendered":"
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Home<\/a><\/span> \/ Intro to RKD<\/a><\/span> \/ Types of RKD<\/a><\/span> \/ Membranous Nephropathy (MN)<\/span><\/span><\/div>\n\n
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Membranous Nephropathy (MN)<\/strong><\/h1>\n\n\n\n

Membranous nephropathy (MN) is a kidney disease that causes injury to the small filters (glomeruli) in kidney tissue. It occurs when the person makes antibodies that damage kidney cells which form part of the kidney filters. Antibodies are proteins produced by the immune system to attack and neutralize harmful bacteria, viruses or other cells. In some cases, antibodies are produced against our own tissues (autoantibodies). The anti-phospholipase A2 receptor (anti-PLA2R) antibody causes more than 60% of cases of MN. Several other antibodies have also been identified in MN. Damage to the kidney filters results in protein leaking into the urine, can reduce the kidneys\u2019 ability to remove waste products from the blood, and over time can irreversibly damage kidney function.<\/p>\n\n\n\n

Medically reviewed by Dr. Jonathan Jefferson, M.D.<\/em><\/p>\n\n<\/div>\n\n

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Who Gets MN<\/h3>\n\n\n\n

Doctors most often diagnose MN in adults, it is a rare disease in children. Most cases of MN only affect the kidneys. In about 25% of cases, Doctors can link MN with other conditions, such as:<\/p>\n\n\n\n

– Cancer
– Medication side effects
– Lupus
– Viral infections<\/p>\n\n<\/div><\/div>\n<\/div>\n<\/div>\n<\/section>\n\n

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Signs and Symptoms<\/h3>\n\n\n
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Some people with MN do not have symptoms. Often, doctors find the condition through routine testing that detects protein in the urine. Other patients may experience swelling and other signs of abnormal kidney function.<\/p>\n\n\n\n

Common signs of MN include:<\/strong><\/p>\n\n\n\n