{"id":28690,"date":"2024-04-11T17:20:45","date_gmt":"2024-04-11T21:20:45","guid":{"rendered":"https:\/\/nephcure.org\/?page_id=28690"},"modified":"2026-07-21T14:39:13","modified_gmt":"2026-07-21T18:39:13","slug":"nefropatia-iga-igan","status":"publish","type":"page","link":"https:\/\/nephcure.org\/es\/intro-to-rkd\/types-of-rkd\/iga-nephropathy-igan\/","title":{"rendered":"Nefropat\u00eda por IgA (NIgA)"},"content":{"rendered":"<section class=\"gb-container gb-container-ba2e2dcb\">\n<div class=\"yoast-breadcrumbs breadcrumb\"><span><span><a href=\"https:\/\/nephcure.org\/\">Home<\/a><\/span> \/ <span><a href=\"https:\/\/nephcure.org\/intro-to-rkd\/\">Intro to RKD<\/a><\/span> \/ <span><a href=\"https:\/\/nephcure.org\/intro-to-rkd\/types-of-rkd\/\">Types of RKD<\/a><\/span> \/ <span class=\"breadcrumb_last\" aria-current=\"page\">IgA Nephropathy (IgAN)<\/span><\/span><\/div>\n\n<div class=\"gb-container gb-container-80071c84 hero-copy\">\n\n<h1 class=\"gb-headline gb-headline-6cf43bd0 gb-headline-text hero-content\"><strong>IgA Nephropathy (IgAN)<\/strong><\/h1>\n\n\n\n<p class=\"wp-block-paragraph\">IgA Nephropathy (IgAN) is a kidney disease in which Immunoglobulin A (IgA) builds up in the kidney. IgA is a protein in the blood. IgA is also part of the immune system. Excess IgA can cause inflammation in the kidney. Over time, this leads to scarring in the kidney tissue.&nbsp;The severity of kidney disease caused by IgAN varies from person to person. As IgAN progresses, it reduces the kidneys\u2019 ability to filter waste from the blood.<\/p>\n\n\n\n<p class=\"wp-block-paragraph\"><em>Medically reviewed by Dr. Miriam Chung, M.D.<\/em><\/p>\n\n<\/div>\n\n<div class=\"gb-container gb-container-b45e9505\">\n<div class=\"gb-grid-wrapper gb-grid-wrapper-d4ac8e2d\">\n<div class=\"gb-grid-column gb-grid-column-0dc6618f\"><div class=\"gb-container gb-container-0dc6618f\"><\/div><\/div>\n\n<div class=\"gb-grid-column gb-grid-column-ab8ac5ed\"><div class=\"gb-container gb-container-ab8ac5ed\">\n\n<h3 class=\"gb-headline gb-headline-8b25774b gb-headline-text\">Who Gets IgAN<\/h3>\n\n\n\n<p class=\"wp-block-paragraph\">IgAN can occur at any age. Doctors most often diagnose it in people between 20 and 30 years old. The condition happens mostly in people of East Asian and European ancestry.&nbsp;<\/p>\n\n\n\n<p class=\"gb-headline gb-headline-773751e7 gb-headline-text\"><\/p>\n\n\n\n<div style=\"height:20px\" aria-hidden=\"true\" class=\"wp-block-spacer\"><\/div>\n\n<\/div><\/div>\n<\/div>\n<\/div>\n<\/section>\n\n<div class=\"gb-container gb-container-dd508e5c\">\n<div class=\"gb-container gb-container-c563d239\">\n<div class=\"gb-grid-wrapper gb-grid-wrapper-c8a1e95b\">\n<div class=\"gb-grid-column gb-grid-column-cf6e757b\"><div class=\"gb-container gb-container-cf6e757b\">\n\n<figure class=\"gb-block-image gb-block-image-a7066f5f\"><img loading=\"lazy\" decoding=\"async\" width=\"464\" height=\"441\" class=\"gb-image gb-image-a7066f5f\" src=\"https:\/\/nephcure.org\/wp-content\/uploads\/2024\/04\/33.png\" alt=\"\" title=\"33\" srcset=\"https:\/\/nephcure.org\/wp-content\/uploads\/2024\/04\/33.png 464w, https:\/\/nephcure.org\/wp-content\/uploads\/2024\/04\/33-300x285.png 300w, https:\/\/nephcure.org\/wp-content\/uploads\/2024\/04\/33-13x12.png 13w\" sizes=\"auto, (max-width: 464px) 100vw, 464px\" \/><\/figure>\n\n<\/div><\/div>\n\n<div class=\"gb-grid-column gb-grid-column-5e455c53\"><div class=\"gb-container gb-container-5e455c53\">\n\n<figure class=\"gb-block-image gb-block-image-45999f79\"><img loading=\"lazy\" decoding=\"async\" width=\"54\" height=\"4\" class=\"gb-image gb-image-45999f79\" src=\"https:\/\/nephcure.org\/wp-content\/uploads\/2023\/11\/heading-line.svg\" alt=\"\" title=\"heading-line\"\/><\/figure>\n\n\n\n<h3 class=\"gb-headline gb-headline-c266dc1b gb-headline-text\">Signs and Symptoms<\/h3>\n\n\n<div class=\"gb-container gb-container-c1e3b0aa\"><\/div>\n\n\n<p class=\"wp-block-paragraph\">Symptoms of IgAN are different for every patient. Some symptoms occur even when kidney function blood test results are normal.&nbsp;<\/p>\n\n\n\n<p class=\"wp-block-paragraph\"><strong>Common signs of IgAN include:&nbsp;<\/strong><\/p>\n\n\n\n<ul class=\"wp-block-list\">\n<li>Blood in the urine&nbsp;&nbsp;<\/li>\n\n\n\n<li>Dark or \u201ccola\u201d colored urine after a viral infection (cold, respiratory illness, sore throat)&nbsp;<\/li>\n\n\n\n<li>Blood in urine only detected by a urine test&nbsp;<\/li>\n\n\n\n<li>Protein in the urine&nbsp;<\/li>\n<\/ul>\n\n\n\n<p class=\"wp-block-paragraph\">When IgAN progresses, blood tests for kidney function will show abnormal results. Advanced IgAN kidney disease can lead to kidney failure.<\/p>\n\n<\/div><\/div>\n<\/div>\n<\/div>\n\n<div class=\"gb-container gb-container-69f54528\">\n<div class=\"gb-grid-wrapper gb-grid-wrapper-f6391388\">\n<div class=\"gb-grid-column gb-grid-column-1b251990\"><div class=\"gb-container gb-container-1b251990\">\n\n<figure class=\"gb-block-image gb-block-image-04215775\"><img loading=\"lazy\" decoding=\"async\" width=\"900\" height=\"498\" class=\"gb-image gb-image-04215775\" src=\"https:\/\/nephcure.org\/wp-content\/uploads\/2024\/04\/alternating-columns-1.png\" alt=\"\" title=\"alternating columns 1\" srcset=\"https:\/\/nephcure.org\/wp-content\/uploads\/2024\/04\/alternating-columns-1.png 900w, https:\/\/nephcure.org\/wp-content\/uploads\/2024\/04\/alternating-columns-1-300x166.png 300w, https:\/\/nephcure.org\/wp-content\/uploads\/2024\/04\/alternating-columns-1-768x425.png 768w, https:\/\/nephcure.org\/wp-content\/uploads\/2024\/04\/alternating-columns-1-18x10.png 18w\" sizes=\"auto, (max-width: 900px) 100vw, 900px\" \/><\/figure>\n\n<\/div><\/div>\n\n<div class=\"gb-grid-column gb-grid-column-f6ca6fd4\"><div class=\"gb-container gb-container-f6ca6fd4\">\n\n<figure class=\"gb-block-image gb-block-image-a10aa848\"><img loading=\"lazy\" decoding=\"async\" width=\"54\" height=\"4\" class=\"gb-image gb-image-a10aa848\" src=\"https:\/\/nephcure.org\/wp-content\/uploads\/2023\/11\/heading-line.svg\" alt=\"\" title=\"heading-line\"\/><\/figure>\n\n\n\n<h3 class=\"gb-headline gb-headline-c38aad44 gb-headline-text\">Diagnosing IgAN<\/h3>\n\n\n<div class=\"gb-container gb-container-c1c0889b\"><\/div>\n\n\n<p class=\"wp-block-paragraph\">The only test that can diagnose IgAN is a kidney biopsy.&nbsp;&nbsp;<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">During the procedure, your doctor removes a sample of kidney tissue and studies it under a microscope. Doctors often use a biopsy to confirm a diagnosis after blood and urine tests show signs of the condition.&nbsp;<\/p>\n\n\n\n<ul class=\"wp-block-list\">\n<li>Blood tests can show high levels of waste in the blood, a sign the kidneys are not properly filtering the blood&nbsp;<\/li>\n\n\n\n<li>Urine tests can reveal the presence of blood or protein&nbsp;&nbsp;<\/li>\n<\/ul>\n\n<\/div><\/div>\n<\/div>\n<\/div>\n\n<div class=\"gb-container gb-container-e23189e2\">\n<div class=\"gb-grid-wrapper gb-grid-wrapper-fe9d6ccd\">\n<div class=\"gb-grid-column gb-grid-column-84ff3e7e\"><div class=\"gb-container gb-container-84ff3e7e\">\n\n<figure class=\"gb-block-image gb-block-image-e8e4a274\"><img loading=\"lazy\" decoding=\"async\" width=\"2560\" height=\"1700\" class=\"gb-image gb-image-e8e4a274\" src=\"https:\/\/nephcure.org\/wp-content\/uploads\/2024\/04\/Website-Homepage-Template.png\" alt=\"\" title=\"Website-Homepage-Template\" srcset=\"https:\/\/nephcure.org\/wp-content\/uploads\/2024\/04\/Website-Homepage-Template.png 2560w, https:\/\/nephcure.org\/wp-content\/uploads\/2024\/04\/Website-Homepage-Template-300x199.png 300w, https:\/\/nephcure.org\/wp-content\/uploads\/2024\/04\/Website-Homepage-Template-1024x680.png 1024w, https:\/\/nephcure.org\/wp-content\/uploads\/2024\/04\/Website-Homepage-Template-768x510.png 768w, https:\/\/nephcure.org\/wp-content\/uploads\/2024\/04\/Website-Homepage-Template-1536x1020.png 1536w, https:\/\/nephcure.org\/wp-content\/uploads\/2024\/04\/Website-Homepage-Template-2048x1360.png 2048w, https:\/\/nephcure.org\/wp-content\/uploads\/2024\/04\/Website-Homepage-Template-18x12.png 18w\" sizes=\"auto, (max-width: 2560px) 100vw, 2560px\" \/><\/figure>\n\n<\/div><\/div>\n\n<div class=\"gb-grid-column gb-grid-column-eb1086dc\"><div class=\"gb-container gb-container-eb1086dc\">\n\n<figure class=\"gb-block-image gb-block-image-cb51b2f9\"><img loading=\"lazy\" decoding=\"async\" width=\"54\" height=\"4\" class=\"gb-image gb-image-cb51b2f9\" src=\"https:\/\/nephcure.org\/wp-content\/uploads\/2023\/11\/heading-line.svg\" alt=\"\" title=\"heading-line\"\/><\/figure>\n\n\n\n<h3 class=\"gb-headline gb-headline-076180d2 gb-headline-text\">Your Treatment Options<\/h3>\n\n\n\n<p class=\"wp-block-paragraph\">There is no cure for IgAN. Your doctor may prescribe several treatments to help manage your symptoms. &nbsp;<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">There are currently several FDA-approved therapies for IgAN:<\/p>\n\n\n\n<ul class=\"wp-block-list\">\n<li><a href=\"https:\/\/nephcure.org\/managing-rkd\/treatment-options\/fabhalta-iptacopan\/\" target=\"_blank\" rel=\"noreferrer noopener\">FABHALTA (iptacopan)<\/a><\/li>\n\n\n\n<li><a href=\"https:\/\/nephcure.org\/managing-rkd\/treatment-options\/filspari-sparsentan\/\" target=\"_blank\" rel=\"noreferrer noopener\">FILSPARI (sparsentan)<\/a><\/li>\n\n\n\n<li><a href=\"https:\/\/nephcure.org\/managing-rkd\/treatment-options\/budesonide-tarpeyo\/\" target=\"_blank\" rel=\"noreferrer noopener\">TARPEYO (budesonide)<\/a><\/li>\n\n\n\n<li>TRUTAKNA (atacicept)<\/li>\n\n\n\n<li><a href=\"https:\/\/nephcure.org\/managing-rkd\/treatment-options\/vanrafia-atrasentan\/\" target=\"_blank\" rel=\"noreferrer noopener\">VANRAFIA (atrasentan)<\/a><\/li>\n\n\n\n<li><a href=\"https:\/\/nephcure.org\/managing-rkd\/treatment-options\/voyxact-sibeprenlimab\/\" target=\"_blank\" rel=\"noreferrer noopener\">VOYXACT (sibeprenlimab)<\/a><\/li>\n<\/ul>\n\n\n\n<p class=\"wp-block-paragraph\">Each of these medicines works in a different way to treat IgAN. Your doctor can help you find the treatment that is the right fit for you. Click any name above to learn more about that specific treatment option.<\/p>\n\n<\/div><\/div>\n<\/div>\n\n\n<p class=\"has-text-align-left wp-block-paragraph\">Your nephrologist may use several different strategies to protect your kidneys and slow any damage. These may include:<\/p>\n\n\n\n<ul class=\"wp-block-list\">\n<li><strong>Managing blood pressure.\u00a0<\/strong>Blood pressure control is very important in treating IgAN symptoms. Blood pressure medications such as ACE inhibitors (angiotensin-converting enzymes) or ARBs (angiotensin receptor blockers) can help lower blood pressure and protein in the urine.<\/li>\n\n\n\n<li><strong>Lowering protein in the urine.<\/strong>\u00a0In addition to ACE inhibitors and ARB medicines, doctors may also prescribe other medications to lower urine protein, such as:\n<ul class=\"wp-block-list\">\n<li>SGLT2 inhibitors<\/li>\n\n\n\n<li>Medicines that block endothelin receptors\u00a0<\/li>\n<\/ul>\n<\/li>\n\n\n\n<li><strong>Reducing immune system response.<\/strong>\u00a0Doctors may recommend\u00a0medication (immunomodulator) to lower the overproduction of abnormal antibody (Gd-IgA1) and\/or help calm the kidney inflammation, such as B-cell targeting therapies, targeted-release corticosteroid, and complement inhibitor.\u00a0 \u00a0\u00a0<\/li>\n\n\n\n<li><strong>Participation in clinical trial.<\/strong>\u00a0Some medical centers may have clinical trials for IgAN.\u202f<\/li>\n<\/ul>\n\n<\/div>\n<\/div>\n\n<div class=\"gb-container gb-container-c7966d90\">\n<div class=\"gb-container gb-container-4d8a4fe1\">\n\n<figure class=\"gb-block-image gb-block-image-9ab43e4d\"><img loading=\"lazy\" decoding=\"async\" width=\"54\" height=\"4\" class=\"gb-image gb-image-9ab43e4d\" src=\"https:\/\/nephcure.org\/wp-content\/uploads\/2023\/11\/heading-line.svg\" alt=\"Headline decoration line\" title=\"heading-line\"\/><\/figure>\n\n\n\n<h2 class=\"gb-headline gb-headline-afffeb92 gb-headline-text\">Clinical trials are another treatment option.<\/h2>\n\n\n\n<p class=\"gb-headline gb-headline-14d28465 gb-headline-text\">Your doctor helps you find the right study for you. These trials test more targeted treatments with potentially lower risks of side effects.<br><br>Some clinical trials enroll patients, based on their genetic testing results, to test the effectiveness of precision-based therapies targeted to specific genetic changes.<\/p>\n\n\n\n<a class=\"gb-button gb-button-52ab81c1 gb-button-text gb-button-primary button\" href=\"https:\/\/nephcure.org\/managing-rkd\/clinical-trials\/\">Explore<\/a>\n\n<\/div>\n\n\n<figure class=\"gb-block-image gb-block-image-5eb3ff4b\"><img loading=\"lazy\" decoding=\"async\" width=\"584\" height=\"583\" class=\"gb-image gb-image-5eb3ff4b\" src=\"https:\/\/nephcure.org\/wp-content\/uploads\/2023\/12\/illustration.png\" alt=\"\" title=\"illustration\" srcset=\"https:\/\/nephcure.org\/wp-content\/uploads\/2023\/12\/illustration.png 584w, https:\/\/nephcure.org\/wp-content\/uploads\/2023\/12\/illustration-300x300.png 300w, https:\/\/nephcure.org\/wp-content\/uploads\/2023\/12\/illustration-150x150.png 150w\" sizes=\"auto, (max-width: 584px) 100vw, 584px\" \/><\/figure>\n\n<\/div>\n\n<div class=\"gb-container gb-container-5dba5269\">\n\n<figure class=\"gb-block-image gb-block-image-63925bfe\"><img loading=\"lazy\" decoding=\"async\" width=\"54\" height=\"4\" class=\"gb-image gb-image-63925bfe\" src=\"https:\/\/nephcure.org\/wp-content\/uploads\/2023\/11\/heading-line.svg\" alt=\"\" title=\"heading-line\"\/><\/figure>\n\n\n\n<h2 class=\"gb-headline gb-headline-6144db93 gb-headline-text\">Tips For Living With IgAN<\/h2>\n\n\n\n<p class=\"gb-headline gb-headline-a2abe2fd gb-headline-text\">Patients with IgAN benefit from supportive measures including:<\/p>\n\n\n<div class=\"gb-container gb-container-44b42b9e\">\n<div class=\"gb-grid-wrapper gb-grid-wrapper-f5f75bf0\">\n<div class=\"gb-grid-column gb-grid-column-e37c2bbf\"><div class=\"gb-container gb-container-e37c2bbf\">\n<div class=\"gb-container gb-container-bc0ff6c3\">\n\n<h4 class=\"gb-headline gb-headline-d237c6e7 gb-headline-text\">Exercise<\/h4>\n\n\n\n<p class=\"gb-headline gb-headline-94cc70f1 gb-headline-text\">Regular, moderate activity helps manage your blood pressure and weight and improves your overall well-being.<\/p>\n\n<\/div>\n<\/div><\/div>\n\n<div class=\"gb-grid-column gb-grid-column-1c7441e8\"><div class=\"gb-container gb-container-1c7441e8\">\n<div class=\"gb-container gb-container-ac344a59\">\n\n<h4 class=\"gb-headline gb-headline-136bf5ec gb-headline-text\">Prescription Regimen<\/h4>\n\n\n\n<p class=\"gb-headline gb-headline-df79a8f4 gb-headline-text\">Follow your doctor\u2019s instructions and take your medicines as prescribed.<\/p>\n\n<\/div>\n<\/div><\/div>\n\n<div class=\"gb-grid-column gb-grid-column-4c659ea0\"><div class=\"gb-container gb-container-4c659ea0\">\n<div class=\"gb-container gb-container-cb224451\">\n\n<h4 class=\"gb-headline gb-headline-ab6868a1 gb-headline-text\">Regular Check-Ups<\/h4>\n\n\n\n<p class=\"gb-headline gb-headline-c62e9f89 gb-headline-text\">See your doctor as scheduled to monitor your kidney function and quickly address any changes.<\/p>\n\n<\/div>\n<\/div><\/div>\n<\/div>\n<\/div>\n<\/div>\n\n<div class=\"gb-container gb-container-3dd326cd gb-container-default\">\n\n<figure class=\"gb-block-image gb-block-image-f04b9551\"><img loading=\"lazy\" decoding=\"async\" width=\"54\" height=\"4\" class=\"gb-image gb-image-f04b9551\" src=\"https:\/\/nephcure.org\/wp-content\/uploads\/2023\/11\/heading-line.svg\" alt=\"\" title=\"heading-line\"\/><\/figure>\n\n\n\n<h2 class=\"gb-headline gb-headline-a237975b gb-headline-text\">Kidney Transplant IgA Nephropathy<\/h2>\n\n\n\n<p class=\"has-text-align-center wp-block-paragraph\">When IgAN causes progressive kidney failure, transplantation is the treatment of choice.&nbsp;Doctors use a transplant kidney biopsy to check for recurrent IgAN. The condition appears in 20% to 50% of patients. However, recurrent IgAN is often less severe and may not cause significant kidney disease.<\/p>\n\n<\/div>\n\n<div class=\"gb-container gb-container-2d207e23 gb-container-default\">\n<div class=\"gb-container gb-container-e876eb37 gb-container-default\">\n<div class=\"gb-container gb-container-b4af985f gb-container-default\">\n<div class=\"gb-container gb-container-7e2f8b5a gb-container-default\">\n<div class=\"gb-container gb-container-b826e82b gb-container-default\">\n<div class=\"gb-grid-wrapper gb-grid-wrapper-a63d26ee\">\n<div class=\"gb-grid-column gb-grid-column-829658f4\"><div class=\"gb-container gb-container-829658f4 video-wrapper\">\n\n<figure class=\"wp-block-embed is-type-video is-provider-youtube wp-block-embed-youtube wp-embed-aspect-16-9 wp-has-aspect-ratio\"><div class=\"wp-block-embed__wrapper\">\n<iframe title=\"Living with IgA Nephropathy: The Personal Stories of Four Rare Kidney Disease Patients\" width=\"1200\" height=\"675\" src=\"https:\/\/www.youtube.com\/embed\/Q8p1TNS2rds?feature=oembed\" frameborder=\"0\" allow=\"accelerometer; autoplay; clipboard-write; encrypted-media; gyroscope; picture-in-picture; web-share\" referrerpolicy=\"strict-origin-when-cross-origin\" allowfullscreen><\/iframe>\n<\/div><\/figure>\n\n\n<div class=\"gb-container gb-container-2b99e692 video-btn\">\n\n<svg xmlns=\"http:\/\/www.w3.org\/2000\/svg\" width=\"149\" height=\"149\" viewBox=\"0 0 149 149\" fill=\"none\">\n  <g filter=\"url(#filter0_d_172_269)\">\n    <circle cx=\"74.5\" cy=\"62.5\" r=\"62.5\" fill=\"#F2F2F2\"\/>\n    <path class = \"resource-svg-icon\" d=\"M97.6826 60.7681C99.0159 61.5379 99.0159 63.4624 97.6826 64.2322L64.409 83.4428C63.0756 84.2126 61.409 83.2503 61.409 81.7107L61.409 43.2896C61.409 41.75 63.0756 40.7878 64.409 41.5576L97.6826 60.7681Z\" fill=\"#3AC2BA\"\/>\n  <\/g>\n  <defs>\n    <filter id=\"filter0_d_172_269\" x=\"0\" y=\"0\" width=\"149\" height=\"149\" filterUnits=\"userSpaceOnUse\" color-interpolation-filters=\"sRGB\">\n      <feFlood flood-opacity=\"0\" result=\"BackgroundImageFix\"\/>\n      <feColorMatrix in=\"SourceAlpha\" type=\"matrix\" values=\"0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 127 0\" result=\"hardAlpha\"\/>\n      <feOffset dy=\"12\"\/>\n      <feGaussianBlur stdDeviation=\"6\"\/>\n      <feComposite in2=\"hardAlpha\" operator=\"out\"\/>\n      <feColorMatrix type=\"matrix\" values=\"0 0 0 0 0.00364583 0 0 0 0 0.232447 0 0 0 0 0.291667 0 0 0 0.2 0\"\/>\n      <feBlend mode=\"normal\" in2=\"BackgroundImageFix\" result=\"effect1_dropShadow_172_269\"\/>\n      <feBlend mode=\"normal\" in=\"SourceGraphic\" in2=\"effect1_dropShadow_172_269\" result=\"shape\"\/>\n    <\/filter>\n  <\/defs>\n<\/svg>\n\n<\/div>\n<\/div><\/div>\n\n<div class=\"gb-grid-column gb-grid-column-de769df2\"><div class=\"gb-container gb-container-de769df2\">\n\n<figure class=\"gb-block-image gb-block-image-2d34fc7c\"><img loading=\"lazy\" decoding=\"async\" width=\"54\" height=\"4\" class=\"gb-image gb-image-2d34fc7c\" src=\"https:\/\/nephcure.org\/wp-content\/uploads\/2023\/11\/heading-line.svg\" alt=\"Headline decoration line\" title=\"heading-line\"\/><\/figure>\n\n\n\n<h2 id=\"h-living-with-igan-personal-stories\" class=\"wp-block-heading\" style=\"font-size:25px\"><strong><strong>Living with IgAN: Personal Stories<\/strong><\/strong><\/h2>\n\n\n\n<p class=\"wp-block-paragraph\"><\/p>\n\n\n\n<p class=\"wp-block-paragraph\">IgA Nephropathy (IgAN) is a rare kidney disease that causes inflammation in the kidney\u2019s filtering units, which can result in kidney damage and may lead to kidney failure.&nbsp;<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">For many patients, a journey with IgAN is a difficult one. Hear the stories of patients from different backgrounds and lifestyles who have dealt first-hand the challenges that come with living with a rare kidney disease.&nbsp;<\/p>\n\n\n\n<a class=\"gb-button gb-button-a8161c30 gb-button-text gb-button-primary button\" href=\"https:\/\/www.youtube.com\/@NephCure\" target=\"_blank\" rel=\"noopener noreferrer\">Visit our youtube page<\/a>\n\n<\/div><\/div>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n\n<div class=\"gb-container gb-container-5e4bc7d1 gb-container-default\">\n<div class=\"gb-container gb-container-d6a8c743 gb-container-default\">\n<div class=\"gb-grid-wrapper gb-grid-wrapper-a7aa4f37\">\n<div class=\"gb-grid-column gb-grid-column-f2ae1af4\"><div class=\"gb-container gb-container-f2ae1af4\">\n\n<figure class=\"gb-block-image gb-block-image-2fe6b3f0\"><img loading=\"lazy\" decoding=\"async\" width=\"54\" height=\"4\" class=\"gb-image gb-image-2fe6b3f0\" src=\"https:\/\/nephcure.org\/wp-content\/uploads\/2023\/11\/heading-line.svg\" alt=\"Headline decoration line\" title=\"heading-line\"\/><\/figure>\n\n\n\n<h2 class=\"gb-headline gb-headline-0f62ae32 gb-headline-text\">The IgAN Alliance<\/h2>\n\n\n\n<p class=\"gb-headline gb-headline-a6032a28 gb-headline-text\">Join us in supporting the&nbsp;IgAN Alliance, a bold new initiative launched in 2025 by NephCure to transform the landscape for those affected by IgA Nephropathy (IgAN). <\/p>\n\n\n\n<p class=\"wp-block-paragraph\">Together with advocacy organizations, healthcare professionals, industry partners, and patients and caregivers, the Alliance is dedicated to raising awareness, speeding diagnosis, and improving care pathways.<\/p>\n\n\n\n<a class=\"gb-button gb-button-a3afba25 gb-button-text gb-button-primary button\" href=\"https:\/\/nephcure.org\/intro-to-rkd\/types-of-rkd\/iga-nephropathy-igan\/the-igan-alliance\/\" target=\"_blank\" rel=\"noopener noreferrer\">LEARN MORE<\/a>\n\n<\/div><\/div>\n\n<div class=\"gb-grid-column gb-grid-column-b708f6ce\"><div class=\"gb-container gb-container-b708f6ce\">\n\n<figure class=\"gb-block-image gb-block-image-320c61c3\"><img loading=\"lazy\" decoding=\"async\" width=\"900\" height=\"498\" class=\"gb-image gb-image-320c61c3\" src=\"https:\/\/nephcure.org\/wp-content\/uploads\/2025\/08\/alternating-columnsiganalliance.png\" alt=\"\" title=\"alternating columnsiganalliance\" srcset=\"https:\/\/nephcure.org\/wp-content\/uploads\/2025\/08\/alternating-columnsiganalliance.png 900w, https:\/\/nephcure.org\/wp-content\/uploads\/2025\/08\/alternating-columnsiganalliance-300x166.png 300w, https:\/\/nephcure.org\/wp-content\/uploads\/2025\/08\/alternating-columnsiganalliance-768x425.png 768w, https:\/\/nephcure.org\/wp-content\/uploads\/2025\/08\/alternating-columnsiganalliance-18x10.png 18w, https:\/\/nephcure.org\/wp-content\/uploads\/2025\/08\/alternating-columnsiganalliance-600x332.png 600w\" sizes=\"auto, (max-width: 900px) 100vw, 900px\" \/><\/figure>\n\n<\/div><\/div>\n<\/div>\n<\/div>\n<\/div>\n\n<div class=\"gb-container gb-container-738151cf gb-container-default\">\n<div class=\"gb-grid-wrapper gb-grid-wrapper-4e98223f\">\n<div class=\"gb-grid-column gb-grid-column-e10c9a65\"><div class=\"gb-container gb-container-e10c9a65\">\n<div class=\"gb-container gb-container-bbfc87f2\">\n\n<h2 class=\"gb-headline gb-headline-efd96085 gb-headline-text\">Support<\/h2>\n\n\n\n<p class=\"gb-headline gb-headline-dccdb00d gb-headline-text\">Get help coping with the challenges of living with IgAN through support groups like NephCure. Learn more about our how we can support you.<\/p>\n\n<\/div>\n\n<div class=\"gb-container gb-container-ff536269\"><a class=\"gb-container-link\" href=\"https:\/\/nephcure.org\/support\/\"><\/a>\n\n<p class=\"gb-headline gb-headline-112c4af9\"><span class=\"gb-icon\"><svg fill=\"none\" viewBox=\"0 0 27 24\" height=\"24\" width=\"27\" xmlns=\"http:\/\/www.w3.org\/2000\/svg\"> <path fill=\"#00556B\" d=\"M26.0607 13.0607C26.6464 12.4749 26.6464 11.5251 26.0607 10.9393L16.5147 1.3934C15.9289 0.807611 14.9792 0.807611 14.3934 1.3934C13.8076 1.97919 13.8076 2.92893 14.3934 3.51472L22.8787 12L14.3934 20.4853C13.8076 21.0711 13.8076 22.0208 14.3934 22.6066C14.9792 23.1924 15.9289 23.1924 16.5147 22.6066L26.0607 13.0607ZM0 13.5H25V10.5H0V13.5Z\"><\/path> <\/svg><\/span><\/p>\n\n<\/div>\n<\/div><\/div>\n\n<div class=\"gb-grid-column gb-grid-column-13e3fbe0\"><div class=\"gb-container gb-container-13e3fbe0\">\n<div class=\"gb-container gb-container-615970e0\">\n\n<h2 class=\"gb-headline gb-headline-1f08a998 gb-headline-text\">Nutrition<\/h2>\n\n\n\n<p class=\"gb-headline gb-headline-49809880 gb-headline-text\">Eat a diet low in salt and processed foods to manage your blood pressure and reduce strain on your kidneys. Learn more about a kidney-friendly diet and get our cookbook.<\/p>\n\n<\/div>\n\n<div class=\"gb-container gb-container-5e409e8f\"><a class=\"gb-container-link\" href=\"https:\/\/nephcure.org\/managing-rkd\/diet-and-nutrition\/\"><\/a>\n\n<p class=\"gb-headline gb-headline-7ae3e628\"><span class=\"gb-icon\"><svg fill=\"none\" viewBox=\"0 0 27 24\" height=\"24\" width=\"27\" xmlns=\"http:\/\/www.w3.org\/2000\/svg\"> <path fill=\"#00556B\" d=\"M26.0607 13.0607C26.6464 12.4749 26.6464 11.5251 26.0607 10.9393L16.5147 1.3934C15.9289 0.807611 14.9792 0.807611 14.3934 1.3934C13.8076 1.97919 13.8076 2.92893 14.3934 3.51472L22.8787 12L14.3934 20.4853C13.8076 21.0711 13.8076 22.0208 14.3934 22.6066C14.9792 23.1924 15.9289 23.1924 16.5147 22.6066L26.0607 13.0607ZM0 13.5H25V10.5H0V13.5Z\"><\/path> <\/svg><\/span><\/p>\n\n<\/div>\n<\/div><\/div>\n<\/div>\n<\/div>\n\n<div class=\"gb-container gb-container-5f18cf75\">\n<div class=\"gb-container gb-container-0018102f\">\n\n<figure class=\"gb-block-image gb-block-image-40625f55\"><img loading=\"lazy\" decoding=\"async\" width=\"54\" height=\"4\" class=\"gb-image gb-image-40625f55\" src=\"https:\/\/kidneydevelop.wpengine.com\/wp-content\/uploads\/2023\/11\/heading-line.svg\" alt=\"\" title=\"heading-line\"\/><\/figure>\n\n\n\n<h2 class=\"gb-headline gb-headline-33d24afb gb-headline-text\">Related Resources<\/h2>\n\n\n<div class=\"gb-container gb-container-8a0bd972\">\n\n<div class=\"gb-grid-wrapper gb-grid-wrapper-2bf95862 resource-cards-loop  gb-query-loop-wrapper\" data-posts=\"post\">\n<div class=\"gb-grid-column gb-grid-column-32674dd1 gb-query-loop-item post-38008 post type-post status-publish format-standard has-post-thumbnail hentry category-uncategorized disease-category-focal-segmental-glomerulosclerosis-fsgs resource-type-informational-documents\"><div class=\"gb-container gb-container-32674dd1 resource-loop-card\">\n<div class=\"gb-container gb-container-6abd4867 recourses-grid-card\"><a class=\"gb-container-link\" href=\"https:\/\/nephcure.org\/es\/sparsentan-filspari-for-fsgs-faqs\/\"><\/a>\n<div class=\"gb-container gb-container-98d50fd4 resource-terms-play post-card-thumbnail\">\n<figure class=\"gb-block-image gb-block-image-ca750b16\"><img loading=\"lazy\" decoding=\"async\" width=\"1200\" height=\"675\" src=\"https:\/\/nephcure.org\/wp-content\/uploads\/2024\/05\/Site-Image.jpg\" class=\"gb-image-ca750b16\" alt=\"Nephcure Site Image\" srcset=\"https:\/\/nephcure.org\/wp-content\/uploads\/2024\/05\/Site-Image.jpg 1200w, https:\/\/nephcure.org\/wp-content\/uploads\/2024\/05\/Site-Image-300x169.jpg 300w, https:\/\/nephcure.org\/wp-content\/uploads\/2024\/05\/Site-Image-1024x576.jpg 1024w, https:\/\/nephcure.org\/wp-content\/uploads\/2024\/05\/Site-Image-768x432.jpg 768w, https:\/\/nephcure.org\/wp-content\/uploads\/2024\/05\/Site-Image-18x10.jpg 18w\" sizes=\"auto, (max-width: 1200px) 100vw, 1200px\" \/><\/figure>\n\n<div class=\"gb-container gb-container-55e46ef5 video-btn\">\n\n<svg xmlns=\"http:\/\/www.w3.org\/2000\/svg\" width=\"149\" height=\"149\" viewBox=\"0 0 149 149\" fill=\"none\">\n  <g filter=\"url(#filter0_d_172_269)\">\n    <circle cx=\"74.5\" cy=\"62.5\" r=\"62.5\" fill=\"#F2F2F2\"\/>\n    <path class = \"resource-svg-icon\" d=\"M97.6826 60.7681C99.0159 61.5379 99.0159 63.4624 97.6826 64.2322L64.409 83.4428C63.0756 84.2126 61.409 83.2503 61.409 81.7107L61.409 43.2896C61.409 41.75 63.0756 40.7878 64.409 41.5576L97.6826 60.7681Z\" fill=\"#3AC2BA\"\/>\n  <\/g>\n  <defs>\n    <filter id=\"filter0_d_172_269\" x=\"0\" y=\"0\" width=\"149\" height=\"149\" filterUnits=\"userSpaceOnUse\" color-interpolation-filters=\"sRGB\">\n      <feFlood flood-opacity=\"0\" result=\"BackgroundImageFix\"\/>\n      <feColorMatrix in=\"SourceAlpha\" type=\"matrix\" values=\"0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 127 0\" result=\"hardAlpha\"\/>\n      <feOffset dy=\"12\"\/>\n      <feGaussianBlur stdDeviation=\"6\"\/>\n      <feComposite in2=\"hardAlpha\" operator=\"out\"\/>\n      <feColorMatrix type=\"matrix\" values=\"0 0 0 0 0.00364583 0 0 0 0 0.232447 0 0 0 0 0.291667 0 0 0 0.2 0\"\/>\n      <feBlend mode=\"normal\" in2=\"BackgroundImageFix\" result=\"effect1_dropShadow_172_269\"\/>\n      <feBlend mode=\"normal\" in=\"SourceGraphic\" in2=\"effect1_dropShadow_172_269\" result=\"shape\"\/>\n    <\/filter>\n  <\/defs>\n<\/svg>\n\n<\/div>\n<\/div><style>.post-38008 .recourses-grid-card .video-btn { display : none } <\/style>\n\n<span style=\"color: #c2005d !important;\" class=\"resource-terms-label\">Informational Documents<\/span>\n\n<h4 class=\"gb-headline gb-headline-e0f58ce0 gb-headline-text\">Sparsentan\u00a0(FILSPARI) for FSGS:\u00a0FAQs<\/h4>\n<\/div>\n<\/div><\/div>\n\n<div class=\"gb-grid-column gb-grid-column-32674dd1 gb-query-loop-item post-27575 post type-post status-publish format-standard has-post-thumbnail hentry category-printable-resource tag-cns tag-ins tag-rare-kidney-disease tag-support disease-category-congenital-infantile-nephrotic-syndrome-cns-ins resource-type-fact-sheet\"><div class=\"gb-container gb-container-32674dd1 resource-loop-card\">\n<div class=\"gb-container gb-container-6abd4867 recourses-grid-card\"><a class=\"gb-container-link\" href=\"https:\/\/nephcure.org\/es\/congenital-nephrotic-syndrome-infantile-nephrotic-syndrome\/\"><\/a>\n<div class=\"gb-container gb-container-98d50fd4 resource-terms-play post-card-thumbnail\">\n<figure class=\"gb-block-image gb-block-image-ca750b16\"><img loading=\"lazy\" decoding=\"async\" width=\"340\" height=\"211\" src=\"https:\/\/nephcure.org\/wp-content\/uploads\/2024\/04\/CNSINS.png\" class=\"gb-image-ca750b16\" alt=\"\" srcset=\"https:\/\/nephcure.org\/wp-content\/uploads\/2024\/04\/CNSINS.png 340w, https:\/\/nephcure.org\/wp-content\/uploads\/2024\/04\/CNSINS-300x186.png 300w, https:\/\/nephcure.org\/wp-content\/uploads\/2024\/04\/CNSINS-18x12.png 18w\" sizes=\"auto, (max-width: 340px) 100vw, 340px\" \/><\/figure>\n\n<div class=\"gb-container gb-container-55e46ef5 video-btn\">\n\n<svg xmlns=\"http:\/\/www.w3.org\/2000\/svg\" width=\"149\" height=\"149\" viewBox=\"0 0 149 149\" fill=\"none\">\n  <g filter=\"url(#filter0_d_172_269)\">\n    <circle cx=\"74.5\" cy=\"62.5\" r=\"62.5\" fill=\"#F2F2F2\"\/>\n    <path class = \"resource-svg-icon\" d=\"M97.6826 60.7681C99.0159 61.5379 99.0159 63.4624 97.6826 64.2322L64.409 83.4428C63.0756 84.2126 61.409 83.2503 61.409 81.7107L61.409 43.2896C61.409 41.75 63.0756 40.7878 64.409 41.5576L97.6826 60.7681Z\" fill=\"#3AC2BA\"\/>\n  <\/g>\n  <defs>\n    <filter id=\"filter0_d_172_269\" x=\"0\" y=\"0\" width=\"149\" height=\"149\" filterUnits=\"userSpaceOnUse\" color-interpolation-filters=\"sRGB\">\n      <feFlood flood-opacity=\"0\" result=\"BackgroundImageFix\"\/>\n      <feColorMatrix in=\"SourceAlpha\" type=\"matrix\" values=\"0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 127 0\" result=\"hardAlpha\"\/>\n      <feOffset dy=\"12\"\/>\n      <feGaussianBlur stdDeviation=\"6\"\/>\n      <feComposite in2=\"hardAlpha\" operator=\"out\"\/>\n      <feColorMatrix type=\"matrix\" values=\"0 0 0 0 0.00364583 0 0 0 0 0.232447 0 0 0 0 0.291667 0 0 0 0.2 0\"\/>\n      <feBlend mode=\"normal\" in2=\"BackgroundImageFix\" result=\"effect1_dropShadow_172_269\"\/>\n      <feBlend mode=\"normal\" in=\"SourceGraphic\" in2=\"effect1_dropShadow_172_269\" result=\"shape\"\/>\n    <\/filter>\n  <\/defs>\n<\/svg>\n\n<\/div>\n<\/div><style>.post-27575 .recourses-grid-card .video-btn { display : none } <\/style>\n\n<span style=\"color: #951f97 !important;\" class=\"resource-terms-label\">Fact Sheet<\/span>\n\n<h4 class=\"gb-headline gb-headline-e0f58ce0 gb-headline-text\">Congenital Nephrotic Syndrome &amp; Infantile Nephrotic Syndrome<\/h4>\n<\/div>\n<\/div><\/div>\n\n<div class=\"gb-grid-column gb-grid-column-32674dd1 gb-query-loop-item post-38012 post type-post status-publish format-standard has-post-thumbnail hentry category-video tag-fsgs tag-video resource-type-video\"><div class=\"gb-container gb-container-32674dd1 resource-loop-card\">\n<div class=\"gb-container gb-container-6abd4867 recourses-grid-card\"><a class=\"gb-container-link\" href=\"https:\/\/nephcure.org\/es\/a-first-for-fsgs-patients-what-the-sparsentan-approval-means-for-you\/\"><\/a>\n<div class=\"gb-container gb-container-98d50fd4 resource-terms-play post-card-thumbnail\">\n<figure class=\"gb-block-image gb-block-image-ca750b16\"><img loading=\"lazy\" decoding=\"async\" width=\"2212\" height=\"1126\" src=\"https:\/\/nephcure.org\/wp-content\/uploads\/2026\/04\/a-first-for-fsgs-patients-sparsentan-approval.png\" class=\"gb-image-ca750b16\" alt=\"\" srcset=\"https:\/\/nephcure.org\/wp-content\/uploads\/2026\/04\/a-first-for-fsgs-patients-sparsentan-approval.png 2212w, https:\/\/nephcure.org\/wp-content\/uploads\/2026\/04\/a-first-for-fsgs-patients-sparsentan-approval-300x153.png 300w, https:\/\/nephcure.org\/wp-content\/uploads\/2026\/04\/a-first-for-fsgs-patients-sparsentan-approval-1024x521.png 1024w, https:\/\/nephcure.org\/wp-content\/uploads\/2026\/04\/a-first-for-fsgs-patients-sparsentan-approval-768x391.png 768w, https:\/\/nephcure.org\/wp-content\/uploads\/2026\/04\/a-first-for-fsgs-patients-sparsentan-approval-1536x782.png 1536w, https:\/\/nephcure.org\/wp-content\/uploads\/2026\/04\/a-first-for-fsgs-patients-sparsentan-approval-2048x1043.png 2048w, https:\/\/nephcure.org\/wp-content\/uploads\/2026\/04\/a-first-for-fsgs-patients-sparsentan-approval-18x9.png 18w, https:\/\/nephcure.org\/wp-content\/uploads\/2026\/04\/a-first-for-fsgs-patients-sparsentan-approval-600x305.png 600w\" sizes=\"auto, (max-width: 2212px) 100vw, 2212px\" \/><\/figure>\n\n<div class=\"gb-container gb-container-55e46ef5 video-btn\">\n\n<svg xmlns=\"http:\/\/www.w3.org\/2000\/svg\" width=\"149\" height=\"149\" viewBox=\"0 0 149 149\" fill=\"none\">\n  <g 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La IgA es una prote\u00edna en la sangre. La IgA tambi\u00e9n es... <a title=\"Nefropat\u00eda por IgA (NIgA)\" class=\"read-more\" href=\"https:\/\/nephcure.org\/es\/intro-to-rkd\/types-of-rkd\/iga-nephropathy-igan\/\" aria-label=\"Leer m\u00e1s sobre Nefropat\u00eda IgA (NIgA)\">Leer m\u00e1s<\/a><\/p>","protected":false},"author":12083,"featured_media":22947,"parent":27159,"menu_order":0,"comment_status":"closed","ping_status":"closed","template":"","meta":{"_acf_changed":false,"inline_featured_image":false,"footnotes":""},"disease-category":[255],"topic":[241],"treatment-option":[],"hf_cat_page":[311],"class_list":["post-28690","page","type-page","status-publish","has-post-thumbnail","disease-category-iga-nephropathy-igan","topic-about-rare-kidney-disease"],"acf":[],"yoast_head":"<!-- This site is optimized with the Yoast SEO Premium plugin v28.1 (Yoast SEO v28.1) - https:\/\/yoast.com\/product\/yoast-seo-premium-wordpress\/ -->\n<title>IgA Nephropathy Diagnosis Symptoms, Causes &amp; Treatment<\/title>\n<meta name=\"description\" content=\"Find out how IgA Nephropathy develops and impacts kidney function. 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