{"id":25779,"date":"2024-01-31T09:43:26","date_gmt":"2024-01-31T14:43:26","guid":{"rendered":"https:\/\/nephcure.org\/?page_id=25779"},"modified":"2025-12-11T15:26:59","modified_gmt":"2025-12-11T20:26:59","slug":"budesonida-tarpeyo","status":"publish","type":"page","link":"https:\/\/nephcure.org\/es\/managing-rkd\/treatment-options\/budesonide-tarpeyo\/","title":{"rendered":"TARPEYO (Budesonida)"},"content":{"rendered":"<section class=\"gb-container gb-container-ba2e2dcb\">\n<div class=\"yoast-breadcrumbs breadcrumb\"><span><span><a href=\"https:\/\/nephcure.org\/\">Home<\/a><\/span> \/ <span><a href=\"https:\/\/nephcure.org\/managing-rkd\/\">Managing RKD<\/a><\/span> \/ <span><a href=\"https:\/\/nephcure.org\/managing-rkd\/treatment-options\/\">Treatment Options<\/a><\/span> \/ <span class=\"breadcrumb_last\" aria-current=\"page\">TARPEYO (Budesonide)<\/span><\/span><\/div>\n\n<div class=\"gb-container gb-container-80071c84 hero-copy\">\n\n<h1 class=\"gb-headline gb-headline-6cf43bd0 gb-headline-text hero-content\">TARPEYO (Budesonide)<\/h1>\n\n\n\n<p>TARPEYO (budesonide) Delayed Release Capsules is a recently FDA approved treatment for IgA nephropathy.<\/p>\n\n<\/div>\n<\/section>\n\n<div class=\"gb-container gb-container-a6126eda\">\n\n<figure class=\"gb-block-image gb-block-image-40625f55\"><img loading=\"lazy\" decoding=\"async\" width=\"54\" height=\"4\" class=\"gb-image gb-image-40625f55\" src=\"https:\/\/nephcure.org\/wp-content\/uploads\/2023\/11\/heading-line.svg\" alt=\"\" title=\"heading-line\"\/><\/figure>\n\n\n\n<h2 class=\"gb-headline gb-headline-88096344 gb-headline-text\"><strong>How Does TARPEYO (Budesonide) Delayed Release Capsules<\/strong> <strong>Work?<\/strong><\/h2>\n\n\n\n<p class=\"gb-headline gb-headline-fb79fb92 gb-headline-text\">TARPEYO (Budesonide) Delayed Release Capsules works to lower the amount of IgA in the body. \u202fWhen too much IgA is in the kidneys, it leads to inflammation and damage to the kidney filters. TARPEYO (Budesonide) Delayed Release Capsules works to target the cells in the gut that make IgA. \u202fBy targeting these cells, the amount of IgA in the body (and kidneys) is reduced.<\/p>\n\n\n<div class=\"gb-container gb-container-626eb763\"><\/div>\n\n\n<figure class=\"gb-block-image gb-block-image-8e308869\"><img loading=\"lazy\" decoding=\"async\" width=\"54\" height=\"4\" class=\"gb-image gb-image-8e308869\" src=\"https:\/\/nephcure.org\/wp-content\/uploads\/2023\/11\/heading-line.svg\" alt=\"\" title=\"heading-line\"\/><\/figure>\n\n\n\n<h2 class=\"gb-headline gb-headline-3de92b95 gb-headline-text\"><strong>What Kind of Medication is TARPEYO<\/strong> (Budesonide) Delayed Release Capsules?<\/h2>\n\n\n\n<p class=\"gb-headline gb-headline-fd1cb896 gb-headline-text\">TARPEYO (Budesonide) Delayed Release Capsules is an oral treatment (taken by mouth). It is a corticosteroid, but unlike other steroids (like prednisone), TARPEYO (Budesonide) Delayed Release Capsules is considered a targeted therapy because it works specifically in the gut; it targets the cells that play an important role in IgA nephropathy (IgAN). TARPEYO (Budesonide) Delayed Release Capsules is also the only FDA-approved steroid for IgAN treatment. \u202fOther steroids have systemic (whole body) impact, not targeted.&nbsp;<br>&nbsp;<br>TARPEYO (Budesonide) Delayed Release Capsules is usually taken for 9-months and may be prescribed with other medications, such as blood pressure medication. \u202f<strong>Be sure to discuss with your nephrologist the best treatment plan and options for you.<\/strong><\/p>\n\n\n\n<p><em>*Note: The decision to prescribe a medication is the responsibility of your physician\/medical team based on their evaluation of your condition. The above is meant for informational purposes only. Discuss this information and all information about drugs\/medications with your physician before starting or stopping any medication.<\/em>&nbsp;<\/p>\n\n<\/div>\n\n<div class=\"gb-container gb-container-80f48e60\">\n\n<figure class=\"gb-block-image gb-block-image-639c7bd5\"><img loading=\"lazy\" decoding=\"async\" width=\"54\" height=\"4\" class=\"gb-image gb-image-639c7bd5\" src=\"https:\/\/nephcure.org\/wp-content\/uploads\/2023\/11\/heading-line.svg\" alt=\"\" title=\"heading-line\"\/><\/figure>\n\n\n\n<h2 class=\"gb-headline gb-headline-bff6dfde gb-headline-text\">Frequently Asked Questions<\/h2>\n\n\n<div class=\"gb-container gb-container-3f003111 gb-accordion\">\n<div class=\"gb-container gb-container-342c972d gb-accordion__item\" data-transition=\"slide\">\n\n<button class=\"gb-button gb-button-05b57231 gb-accordion__toggle\" id=\"gb-accordion-toggle-05b57231\"><span class=\"gb-button-text\"><strong>What does the research say about TARPEYO<\/strong> (Budesonide) Delayed Release Capsules?<\/span><span class=\"gb-icon\"><svg xmlns=\"http:\/\/www.w3.org\/2000\/svg\" viewBox=\"0 0 448 512\" width=\"1em\" height=\"1em\" ariahidden=\"true\" role=\"img\" class=\"gb-accordion__icon\"><path d=\"M416 208H272V64c0-17.67-14.33-32-32-32h-32c-17.67 0-32 14.33-32 32v144H32c-17.67 0-32 14.33-32 32v32c0 17.67 14.33 32 32 32h144v144c0 17.67 14.33 32 32 32h32c17.67 0 32-14.33 32-32V304h144c17.67 0 32-14.33 32-32v-32c0-17.67-14.33-32-32-32z\" fill=\"currentColor\"><\/path><\/svg><svg xmlns=\"http:\/\/www.w3.org\/2000\/svg\" viewBox=\"0 0 448 512\" width=\"1em\" height=\"1em\" ariahidden=\"true\" role=\"img\" class=\"gb-accordion__icon-open\"><path d=\"M416 208H32c-17.67 0-32 14.33-32 32v32c0 17.67 14.33 32 32 32h384c17.67 0 32-14.33 32-32v-32c0-17.67-14.33-32-32-32z\" fill=\"currentColor\"><\/path><\/svg><\/span><\/button>\n\n\n<div id=\"gb-accordion-content-f9fdcd74\" class=\"gb-accordion__content\"><div class=\"gb-container gb-container-f9fdcd74\">\n\n<p>TARPEYO (Budesonide) Delayed Release Capsules has been studied in clinical trials. \u202fUnlike many other treatments used for management of other diseases, TARPEYO (Budesonide) Delayed Release Capsules has been studied specifically in IgAN. \u202fThe clinical trials compared patients prescribed TARPEYO (Budesonide) Delayed Release Capsules with blood pressure medication to patients taking placebo (non-active medication) with blood pressure medication. \u202fThe patients prescribed TARPEYO (Budesonide) Delayed Release Capsules (with blood pressure medication) had significantly lowered levels of protein in their urine.<\/p>\n\n<\/div><\/div>\n<\/div>\n\n<div class=\"gb-container gb-container-2fcf7640 gb-accordion__item\" data-transition=\"slide\">\n\n<button class=\"gb-button gb-button-69efb835 gb-accordion__toggle\" id=\"gb-accordion-toggle-69efb835\"><span class=\"gb-button-text\"><strong>What are the side effects of TARPEYO<\/strong> (Budesonide) Delayed Release Capsules?<\/span><span class=\"gb-icon\"><svg xmlns=\"http:\/\/www.w3.org\/2000\/svg\" viewBox=\"0 0 448 512\" width=\"1em\" height=\"1em\" ariahidden=\"true\" role=\"img\" class=\"gb-accordion__icon\"><path d=\"M416 208H272V64c0-17.67-14.33-32-32-32h-32c-17.67 0-32 14.33-32 32v144H32c-17.67 0-32 14.33-32 32v32c0 17.67 14.33 32 32 32h144v144c0 17.67 14.33 32 32 32h32c17.67 0 32-14.33 32-32V304h144c17.67 0 32-14.33 32-32v-32c0-17.67-14.33-32-32-32z\" fill=\"currentColor\"><\/path><\/svg><svg xmlns=\"http:\/\/www.w3.org\/2000\/svg\" viewBox=\"0 0 448 512\" width=\"1em\" height=\"1em\" ariahidden=\"true\" role=\"img\" class=\"gb-accordion__icon-open\"><path d=\"M416 208H32c-17.67 0-32 14.33-32 32v32c0 17.67 14.33 32 32 32h384c17.67 0 32-14.33 32-32v-32c0-17.67-14.33-32-32-32z\" fill=\"currentColor\"><\/path><\/svg><\/span><\/button>\n\n\n<div id=\"gb-accordion-content-7a4bb49d\" class=\"gb-accordion__content\"><div class=\"gb-container gb-container-7a4bb49d\">\n\n<p>Based on report of the participants in the clinical studies, the side effects of TARPEYO (Budesonide) Delayed Release Capsules may include:&nbsp;<br>\u2022 High blood pressure&nbsp;<br>\u2022 Edema or swelling of the face, legs, ankle or feet&nbsp;<br>\u2022 Muscle cramps&nbsp;<br>\u2022 Weight gain&nbsp;<br>\u2022 Fatigue&nbsp;<br>\u2022 Skin changes, such as acne, skin inflammation or irritation&nbsp;<br>\u2022 Shortness of breath&nbsp;<br>\u2022 Indigestion, such as nausea, vomiting, gas, constipation or diarrhea&nbsp;<br>\u2022 Increase in hair on your body and face<\/p>\n\n<\/div><\/div>\n<\/div>\n\n<div class=\"gb-container gb-container-68f0eaa5 gb-accordion__item\" data-transition=\"slide\">\n\n<button class=\"gb-button gb-button-d702eeea gb-accordion__toggle\" id=\"gb-accordion-toggle-d702eeea\"><span class=\"gb-button-text\"><strong>What should I know before taking TARPEYO<\/strong> (Budesonide) Delayed Release Capsules?<\/span><span class=\"gb-icon\"><svg xmlns=\"http:\/\/www.w3.org\/2000\/svg\" viewBox=\"0 0 448 512\" width=\"1em\" height=\"1em\" ariahidden=\"true\" role=\"img\" class=\"gb-accordion__icon\"><path d=\"M416 208H272V64c0-17.67-14.33-32-32-32h-32c-17.67 0-32 14.33-32 32v144H32c-17.67 0-32 14.33-32 32v32c0 17.67 14.33 32 32 32h144v144c0 17.67 14.33 32 32 32h32c17.67 0 32-14.33 32-32V304h144c17.67 0 32-14.33 32-32v-32c0-17.67-14.33-32-32-32z\" fill=\"currentColor\"><\/path><\/svg><svg xmlns=\"http:\/\/www.w3.org\/2000\/svg\" viewBox=\"0 0 448 512\" width=\"1em\" height=\"1em\" ariahidden=\"true\" role=\"img\" class=\"gb-accordion__icon-open\"><path d=\"M416 208H32c-17.67 0-32 14.33-32 32v32c0 17.67 14.33 32 32 32h384c17.67 0 32-14.33 32-32v-32c0-17.67-14.33-32-32-32z\" fill=\"currentColor\"><\/path><\/svg><\/span><\/button>\n\n\n<div id=\"gb-accordion-content-2b8161d3\" class=\"gb-accordion__content\"><div class=\"gb-container gb-container-2b8161d3\">\n\n<p>Some things to consider while taking TARPEYO (Budesonide) Delayed Release Capsules include:&nbsp;<br>\u2022 Do NOT eat grapefruit and drink grapefruit juice. \u202fGrapefruit can cause higher levels of TARPEYO (Budesonide) Delayed Release Capsules in your blood.&nbsp;<br>\u2022 As a steroid, TARPEYO (Budesonide) Delayed Release Capsules weakens your immune system. \u202fThis means you may be at increased risk of infection or getting sick. \u202fTalk to your doctor about your vaccines and what to do if you think you may have been in contact with someone who has a contagious illness.&nbsp;<\/p>\n\n<\/div><\/div>\n<\/div>\n<\/div>\n<\/div>\n\n<div class=\"gb-container gb-container-0d21e4ac\">\n<div class=\"gb-grid-wrapper gb-grid-wrapper-3d338a55\">\n<div class=\"gb-grid-column gb-grid-column-296a2c84\"><div class=\"gb-container gb-container-296a2c84\">\n<div class=\"gb-container gb-container-eb83049f\">\n\n<h2 class=\"gb-headline gb-headline-5127a4de gb-headline-text\">Find a Specialist<\/h2>\n\n\n\n<p class=\"gb-headline gb-headline-00d5119d gb-headline-text\">It is important to work with a nephrologist who specializes in rare kidney disease (RKD) and can provide personalized advice based on your individual health needs and changes in available treatments. NephCure has a curated list of NephCure Specialists nationwide ready to help you.<\/p>\n\n<\/div>\n\n<div class=\"gb-container gb-container-54aa31c0\"><a class=\"gb-container-link\" href=\"https:\/\/nephcure.org\/managing-rkd\/find-a-specialist\/\"><\/a>\n\n<p class=\"gb-headline gb-headline-38137575\"><span class=\"gb-icon\"><svg fill=\"none\" viewBox=\"0 0 27 24\" height=\"24\" width=\"27\" xmlns=\"http:\/\/www.w3.org\/2000\/svg\"> <path fill=\"#00556B\" d=\"M26.0607 13.0607C26.6464 12.4749 26.6464 11.5251 26.0607 10.9393L16.5147 1.3934C15.9289 0.807611 14.9792 0.807611 14.3934 1.3934C13.8076 1.97919 13.8076 2.92893 14.3934 3.51472L22.8787 12L14.3934 20.4853C13.8076 21.0711 13.8076 22.0208 14.3934 22.6066C14.9792 23.1924 15.9289 23.1924 16.5147 22.6066L26.0607 13.0607ZM0 13.5H25V10.5H0V13.5Z\"><\/path> <\/svg><\/span><\/p>\n\n<\/div>\n<\/div><\/div>\n\n<div class=\"gb-grid-column gb-grid-column-00512214\"><div class=\"gb-container gb-container-00512214\">\n<div class=\"gb-container gb-container-178632bb\">\n\n<h2 class=\"gb-headline gb-headline-74b009b0 gb-headline-text\">Clinical Trials<\/h2>\n\n\n\n<p class=\"has-secondary-lighter-gray-color has-text-color has-link-color wp-elements-6bb4aec7a7f561f2b664a676c9d49fc4\">From accessing cutting-edge treatments to being part of groundbreaking research, discover the benefits that can make a real difference. Learn more about clinical trials currently taking place, and find opportunities near you.<\/p>\n\n<\/div>\n\n<div class=\"gb-container gb-container-e263f928\"><a class=\"gb-container-link\" href=\"https:\/\/nephcure.org\/managing-rkd\/clinical-trials\/\"><\/a>\n\n<p class=\"gb-headline gb-headline-7dbd95e4\"><span class=\"gb-icon\"><svg fill=\"none\" viewBox=\"0 0 27 24\" height=\"24\" width=\"27\" xmlns=\"http:\/\/www.w3.org\/2000\/svg\"> <path fill=\"#00556B\" d=\"M26.0607 13.0607C26.6464 12.4749 26.6464 11.5251 26.0607 10.9393L16.5147 1.3934C15.9289 0.807611 14.9792 0.807611 14.3934 1.3934C13.8076 1.97919 13.8076 2.92893 14.3934 3.51472L22.8787 12L14.3934 20.4853C13.8076 21.0711 13.8076 22.0208 14.3934 22.6066C14.9792 23.1924 15.9289 23.1924 16.5147 22.6066L26.0607 13.0607ZM0 13.5H25V10.5H0V13.5Z\"><\/path> <\/svg><\/span><\/p>\n\n<\/div>\n<\/div><\/div>\n<\/div>\n<\/div>\n\n<div class=\"gb-container gb-container-42105b23 news-letter-sec alignfull\">\n\n<figure class=\"gb-block-image gb-block-image-b3f3ccb8\"><img loading=\"lazy\" decoding=\"async\" width=\"1920\" height=\"120\" class=\"gb-image gb-image-b3f3ccb8\" src=\"https:\/\/nephcure.org\/wp-content\/uploads\/2023\/11\/purple-curve.svg\" alt=\"\" title=\"purple-curve\"\/><\/figure>\n\n\n<div class=\"gb-container gb-container-41717e70 alignwide\">\n\n<h2 class=\"gb-headline gb-headline-1760ac29 gb-headline-text\">Sign up to get NephCure\u2019s latest updates.<\/h2>\n\n\n\n<a class=\"gb-button gb-button-753f318a gb-button-text gb-button-primary button\" href=\"\/newsletter\/\">SIGN UP<\/a>\n\n\n<div class=\"gb-container gb-container-2b968bcb news-letter-field\">\n    <script type=\"text\/javascript\">\n    jQuery(document).ready(function($) {\n        const disposableDomains = [\n            'mailinator.com', 'yopmail.com', 'tempmail.com', 'guerrillamail.com',\n            'throwawaymail.com', 'fakeinbox.com', 'trashmail.com', 'sharklasers.com',\n            'tempinbox.com', '10minutemail.com'\n        ];\n        const majorProviders = [\n            'gmail.com', 'yahoo.com', 'hotmail.com', 'outlook.com',\n            'aol.com', 'icloud.com', 'protonmail.com'\n        ];\n        const suspiciousUsernames = [\n            'test', 'example', 'user', 'admin', 'info', 'mail', 'email',\n            'noreply', 'no-reply', 'donotreply', 'do-not-reply', 'fake',\n            'abc', '123', 'xyz', 'asdf', 'qwerty', 'demo', 'sample',\n            'spam', 'temp', 'dummy', 'foobar', 'anonymous', 'disposable'\n        ];\n        const keyboardPatterns = ['qwerty', 'asdfgh', 'zxcvbn', '123456'];\n\n        function isValidEmailFormat(email) {\n            const regex = \/^[^\\s@]+@[^\\s@]+\\.[^\\s@]+$\/;\n            return regex.test(email);\n        }\n\n        function hasSuspiciousPattern(username) {\n            if (suspiciousUsernames.includes(username)) return true;\n            if (username.length <= 2) return true;\n            if (\/^(.)\\1{3,}$\/.test(username)) return true;\n            for (const pattern of keyboardPatterns) {\n                if (username.includes(pattern)) return true;\n            }\n            return false;\n        }\n\n        function usernameMatchesDomain(username, domain) {\n            const domainBase = domain.split('.')[0];\n            return username === domainBase;\n        }\n\n        $('.ginput_container_email input').on('blur', function() {\n            const emailField = $(this);\n            const email = emailField.val().trim().toLowerCase();\n            const errorContainer = emailField.siblings('.validation_message');\n\n            \/\/ Clear any previous messages\n            if (errorContainer.length) errorContainer.remove();\n            emailField.removeClass('gfield_error gfield_warning');\n\n            if (email === '') return;\n\n            const username = email.substring(0, email.lastIndexOf('@'));\n            const domain = email.substring(email.lastIndexOf('@') + 1);\n\n            if (!isValidEmailFormat(email)) {\n                emailField.after('<div class=\"validation_message\">Please enter a valid email address.<\/div>');\n                emailField.addClass('gfield_error');\n                return;\n            }\n\n            if (disposableDomains.includes(domain)) {\n                emailField.after('<div class=\"validation_message\">Disposable email addresses are not allowed.<\/div>');\n                emailField.addClass('gfield_error');\n                return;\n            }\n\n            if (usernameMatchesDomain(username, domain)) {\n                emailField.after('<div class=\"validation_message\">This email looks suspicious (username matches domain). 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