{"id":25769,"date":"2024-01-31T09:36:00","date_gmt":"2024-01-31T14:36:00","guid":{"rendered":"https:\/\/nephcure.org\/?page_id=25769"},"modified":"2024-08-29T12:03:14","modified_gmt":"2024-08-29T16:03:14","slug":"inhibidores-de-ace","status":"publish","type":"page","link":"https:\/\/nephcure.org\/es\/managing-rkd\/treatment-options\/ace-inhibitors\/","title":{"rendered":"Inhibidores de la ECA"},"content":{"rendered":"<section class=\"gb-container gb-container-ba2e2dcb\">\n<div class=\"yoast-breadcrumbs breadcrumb\"><span><span><a href=\"https:\/\/nephcure.org\/\">Home<\/a><\/span> \/ <span><a href=\"https:\/\/nephcure.org\/managing-rkd\/\">Managing RKD<\/a><\/span> \/ <span><a href=\"https:\/\/nephcure.org\/managing-rkd\/treatment-options\/\">Treatment Options<\/a><\/span> \/ <span class=\"breadcrumb_last\" aria-current=\"page\">ACE Inhibitors<\/span><\/span><\/div>\n\n<div class=\"gb-container gb-container-80071c84 hero-copy\">\n\n<h1 class=\"gb-headline gb-headline-6cf43bd0 gb-headline-text hero-content\">ACE Inhibitors<\/h1>\n\n\n\n<p class=\"wp-block-paragraph\">An ACE inhibitor (or angiotensin converting enzyme inhibitor) is a medication used primarily for the treatment of heart, blood vessel, and kidney problems.<\/p>\n\n<\/div>\n<\/section>\n\n<div class=\"gb-container gb-container-a6126eda\">\n\n<figure class=\"gb-block-image gb-block-image-40625f55\"><img loading=\"lazy\" decoding=\"async\" width=\"54\" height=\"4\" class=\"gb-image gb-image-40625f55\" src=\"https:\/\/nephcure.org\/wp-content\/uploads\/2023\/11\/heading-line.svg\" alt=\"\" title=\"heading-line\"\/><\/figure>\n\n\n\n<h2 class=\"gb-headline gb-headline-88096344 gb-headline-text\">How does an ACE inhibitor work?<\/h2>\n\n\n\n<p class=\"gb-headline gb-headline-fb79fb92 gb-headline-text\">ACE inhibitors prevent an enzyme in your body from producing angiotensin II, a substance that affects your cardiovascular system by narrowing your blood vessels and releasing hormones that can raise your blood pressure. This narrowing can cause high blood pressure and force your heart to work harder. ACE inhibitors also increase blood flow, which helps to decrease the amount of work your heart has to do and can help protect your kidneys from the effects of hypertension (high blood pressure).<\/p>\n\n\n<div class=\"gb-container gb-container-626eb763\"><\/div>\n\n\n<figure class=\"gb-block-image gb-block-image-b5077fe4\"><img loading=\"lazy\" decoding=\"async\" width=\"54\" height=\"4\" class=\"gb-image gb-image-b5077fe4\" src=\"https:\/\/nephcure.org\/wp-content\/uploads\/2023\/11\/heading-line.svg\" alt=\"\" title=\"heading-line\"\/><\/figure>\n\n\n\n<h2 class=\"gb-headline gb-headline-3de92b95 gb-headline-text\">What are the different types of ACE inhibitors?<\/h2>\n\n\n\n<p class=\"wp-block-paragraph\">There are many different names and brands of ACE inhibitors. Examples of ACE inhibitors include:<\/p>\n\n\n\n<ul class=\"wp-block-list\">\n<li>Benazepril (Lotensin)<\/li>\n\n\n\n<li>Captopril<\/li>\n\n\n\n<li>Enalapril (Vasotec)<\/li>\n\n\n\n<li>Fosinopril<\/li>\n\n\n\n<li>Lisinopril (Prinivil, Zestril)<\/li>\n\n\n\n<li>Moexipril (Univasc)<\/li>\n\n\n\n<li>Perindopril (Aceon)<\/li>\n\n\n\n<li>Quinapril (Accupril)<\/li>\n\n\n\n<li>Ramipril (Altace)<\/li>\n\n\n\n<li>Trandolapril (Mavik)<\/li>\n<\/ul>\n\n\n\n<figure class=\"gb-block-image gb-block-image-64151c6a\"><img loading=\"lazy\" decoding=\"async\" width=\"54\" height=\"4\" class=\"gb-image gb-image-64151c6a\" src=\"https:\/\/nephcure.org\/wp-content\/uploads\/2023\/11\/heading-line.svg\" alt=\"\" title=\"heading-line\"\/><\/figure>\n\n\n\n<h2 class=\"gb-headline gb-headline-6006a81b gb-headline-text\">For what conditions are ACE inhibitors used?<\/h2>\n\n\n\n<p class=\"wp-block-paragraph\">Doctors prescribe ACE inhibitors to prevent, treat or improve symptoms in conditions such as:<\/p>\n\n\n\n<ul class=\"wp-block-list\">\n<li>High blood pressure<\/li>\n\n\n\n<li>Coronary artery disease<\/li>\n\n\n\n<li>Heart failure<\/li>\n\n\n\n<li>Diabetes<\/li>\n\n\n\n<li>Certain chronic kidney diseases (primary nephrotic syndrome)<\/li>\n\n\n\n<li>Heart attacks<\/li>\n\n\n\n<li>Migraines<\/li>\n<\/ul>\n\n\n\n<p class=\"gb-headline gb-headline-8aeb36c5 gb-headline-text\"><br><\/p>\n\n\n\n<p class=\"wp-block-paragraph\">In studies, individuals with hypertension (high blood pressure), heart failure or prior heart attacks that were treated with an ACE inhibitor lived longer than patients who did not take an ACE inhibitor. However, some individuals with hypertension do not respond sufficiently to ACE inhibitors alone. In these cases, other drugs are used in combination with ACE inhibitors.<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">ACE inhibitors are regularly prescribed for patients diagnosed with primary (idiopathic) Nephrotic Syndrome in order to manage high blood pressure as a result of malfunctioning kidneys leading to fluid retention or overload.<br>Are there any differences among the different types of ACE inhibitors?<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">ACE inhibitors are very similar. However, they differ in how they are eliminated from the body and their doses. Some ACE inhibitors need to be converted into an active form in the body before they work. In addition, some ACE inhibitors may work more on the ACE (angiotensin converting enzyme) that is present in tissues than on ACE that is present in the blood.<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">The importance of this difference or whether one ACE inhibitor is better than another has not been determined. Many seem to work equally as well. Your physician will prescribe what he\/she thinks will work best for your condition based on experience. Side effects may vary for different ones.<\/p>\n\n\n\n<p class=\"wp-block-paragraph\"><em>*Note: The decision to prescribe a medication is the responsibility of your physician\/primary care provider based on his\/her evaluation of your condition. The above is meant for informational purposes only. Discuss this information and all information about drugs\/medications with your physician before starting or stopping any medication.<\/em><\/p>\n\n<\/div>\n\n<div class=\"gb-container gb-container-80f48e60\">\n\n<figure class=\"gb-block-image gb-block-image-38d5ed74\"><img loading=\"lazy\" decoding=\"async\" width=\"54\" height=\"4\" class=\"gb-image gb-image-38d5ed74\" src=\"https:\/\/nephcure.org\/wp-content\/uploads\/2023\/11\/heading-line.svg\" alt=\"\" title=\"heading-line\"\/><\/figure>\n\n\n\n<h2 class=\"gb-headline gb-headline-bff6dfde gb-headline-text\">Frequently Asked Questions<\/h2>\n\n\n<div class=\"gb-container gb-container-3f003111 gb-accordion\">\n<div class=\"gb-container gb-container-342c972d gb-accordion__item\" data-transition=\"slide\">\n\n<button class=\"gb-button gb-button-05b57231 gb-accordion__toggle\" id=\"gb-accordion-toggle-05b57231\"><span class=\"gb-button-text\">How is an ACE inhibitor administered?<\/span><span class=\"gb-icon\"><svg xmlns=\"http:\/\/www.w3.org\/2000\/svg\" viewBox=\"0 0 448 512\" width=\"1em\" height=\"1em\" ariahidden=\"true\" role=\"img\" class=\"gb-accordion__icon\"><path d=\"M416 208H272V64c0-17.67-14.33-32-32-32h-32c-17.67 0-32 14.33-32 32v144H32c-17.67 0-32 14.33-32 32v32c0 17.67 14.33 32 32 32h144v144c0 17.67 14.33 32 32 32h32c17.67 0 32-14.33 32-32V304h144c17.67 0 32-14.33 32-32v-32c0-17.67-14.33-32-32-32z\" fill=\"currentColor\"><\/path><\/svg><svg xmlns=\"http:\/\/www.w3.org\/2000\/svg\" viewBox=\"0 0 448 512\" width=\"1em\" height=\"1em\" ariahidden=\"true\" role=\"img\" class=\"gb-accordion__icon-open\"><path d=\"M416 208H32c-17.67 0-32 14.33-32 32v32c0 17.67 14.33 32 32 32h384c17.67 0 32-14.33 32-32v-32c0-17.67-14.33-32-32-32z\" fill=\"currentColor\"><\/path><\/svg><\/span><\/button>\n\n\n<div id=\"gb-accordion-content-f9fdcd74\" class=\"gb-accordion__content\"><div class=\"gb-container gb-container-f9fdcd74\">\n\n<p class=\"wp-block-paragraph\">ACE inhibitors are pills that you take by mouth. ACE inhibitors are usually taken once daily, and many people take them in the morning. Try to take your medications at the same time, or times, each day. Do not stop taking your medicines without talking with your doctor first.<\/p>\n\n<\/div><\/div>\n<\/div>\n\n<div class=\"gb-container gb-container-2fcf7640 gb-accordion__item\" data-transition=\"slide\">\n\n<button class=\"gb-button gb-button-69efb835 gb-accordion__toggle\" id=\"gb-accordion-toggle-69efb835\"><span class=\"gb-button-text\">What are the side effects of ACE inhibitors?<\/span><span class=\"gb-icon\"><svg xmlns=\"http:\/\/www.w3.org\/2000\/svg\" viewBox=\"0 0 448 512\" width=\"1em\" height=\"1em\" ariahidden=\"true\" role=\"img\" class=\"gb-accordion__icon\"><path d=\"M416 208H272V64c0-17.67-14.33-32-32-32h-32c-17.67 0-32 14.33-32 32v144H32c-17.67 0-32 14.33-32 32v32c0 17.67 14.33 32 32 32h144v144c0 17.67 14.33 32 32 32h32c17.67 0 32-14.33 32-32V304h144c17.67 0 32-14.33 32-32v-32c0-17.67-14.33-32-32-32z\" fill=\"currentColor\"><\/path><\/svg><svg xmlns=\"http:\/\/www.w3.org\/2000\/svg\" viewBox=\"0 0 448 512\" width=\"1em\" height=\"1em\" ariahidden=\"true\" role=\"img\" class=\"gb-accordion__icon-open\"><path d=\"M416 208H32c-17.67 0-32 14.33-32 32v32c0 17.67 14.33 32 32 32h384c17.67 0 32-14.33 32-32v-32c0-17.67-14.33-32-32-32z\" fill=\"currentColor\"><\/path><\/svg><\/span><\/button>\n\n\n<div id=\"gb-accordion-content-7a4bb49d\" class=\"gb-accordion__content\"><div class=\"gb-container gb-container-7a4bb49d\">\n\n<p class=\"wp-block-paragraph\">ACE inhibitors are well-tolerated by most individuals. Nevertheless, they are not free of side effects, and some patients should not use ACE inhibitors. You should discuss the benefits and risks of all medications with your physician.<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">ACE inhibitors usually are not prescribed for pregnant patients because they may cause birth defects. Individuals with bilateral (two-sided) renal artery stenosis (narrowing of blood vessels in the kidneys) may experience worsening of kidney function. People who have had a severe reaction to ACE inhibitors should avoid them.<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">The most common side effects are:<\/p>\n\n\n\n<ul class=\"wp-block-list\">\n<li>Chronic cough<\/li>\n\n\n\n<li>Elevated blood potassium levels<\/li>\n\n\n\n<li>Low blood pressure<\/li>\n\n\n\n<li>Dizziness<\/li>\n\n\n\n<li>Headache<\/li>\n\n\n\n<li>Drowsiness<\/li>\n\n\n\n<li>Weakness<\/li>\n\n\n\n<li>Abnormal taste (metallic or salty taste)<\/li>\n\n\n\n<li>Rash<\/li>\n\n\n\n<li>It may take up to a month for coughing to subside, and if one ACE inhibitor causes a cough it is likely that the others will too.<\/li>\n<\/ul>\n\n\n\n<p class=\"wp-block-paragraph\">The most serious, but rare, side effects of ACE inhibitors are:<\/p>\n\n\n\n<ul class=\"wp-block-list\">\n<li>Kidney failure<\/li>\n\n\n\n<li>Allergic reactions<\/li>\n\n\n\n<li>Decrease in white blood cells<\/li>\n\n\n\n<li>Marked swelling of tissues (angioedema)<\/li>\n<\/ul>\n\n<\/div><\/div>\n<\/div>\n\n<div class=\"gb-container gb-container-68f0eaa5 gb-accordion__item\" data-transition=\"slide\">\n\n<button class=\"gb-button gb-button-d702eeea gb-accordion__toggle\" id=\"gb-accordion-toggle-d702eeea\"><span class=\"gb-button-text\">What other medications do ACE inhibitors interact?<\/span><span class=\"gb-icon\"><svg xmlns=\"http:\/\/www.w3.org\/2000\/svg\" viewBox=\"0 0 448 512\" width=\"1em\" height=\"1em\" ariahidden=\"true\" role=\"img\" class=\"gb-accordion__icon\"><path d=\"M416 208H272V64c0-17.67-14.33-32-32-32h-32c-17.67 0-32 14.33-32 32v144H32c-17.67 0-32 14.33-32 32v32c0 17.67 14.33 32 32 32h144v144c0 17.67 14.33 32 32 32h32c17.67 0 32-14.33 32-32V304h144c17.67 0 32-14.33 32-32v-32c0-17.67-14.33-32-32-32z\" fill=\"currentColor\"><\/path><\/svg><svg xmlns=\"http:\/\/www.w3.org\/2000\/svg\" viewBox=\"0 0 448 512\" width=\"1em\" height=\"1em\" ariahidden=\"true\" role=\"img\" class=\"gb-accordion__icon-open\"><path d=\"M416 208H32c-17.67 0-32 14.33-32 32v32c0 17.67 14.33 32 32 32h384c17.67 0 32-14.33 32-32v-32c0-17.67-14.33-32-32-32z\" fill=\"currentColor\"><\/path><\/svg><\/span><\/button>\n\n\n<div id=\"gb-accordion-content-2b8161d3\" class=\"gb-accordion__content\"><div class=\"gb-container gb-container-2b8161d3\">\n\n<p class=\"wp-block-paragraph\">ACE inhibitors have few interactions with other drugs. Since ACE inhibitors may increase blood levels of potassium, the use of potassium supplements, salt substitutes (which often contain potassium), or other drugs that increase the body\u2019s potassium may result in excessive blood potassium levels.<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">There have been reports that aspirin and other non-steroidal anti-inflammatory drugs (NSAIDS) such as ibuprofen (Advil, Children\u2019s Advil\/Motrin, Medipren, Motrin, Nuprin, PediaCare Fever etc.), indomethacin (Indocin, Indocin-SR), and naproxen (Anaprox, Naprelan, Naprosyn, Aleve) may reduce the effects of ACE inhibitors.<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">ACE inhibitors also may increase the blood concentration of lithium (Eskalith) and lead to an increase in side effects from lithium.<\/p>\n\n\n\n<h5 class=\"wp-block-heading\" id=\"h-other-important-tips\">Other important tips:<\/h5>\n\n\n\n<ul class=\"wp-block-list\">\n<li>Before taking ibuprofen (Advil, Motrin) or aspirin, talk to your doctor.<\/li>\n\n\n\n<li>Tell your doctor what other medicines you are taking. This includes over the counter drugs, diuretics (water pills), potassium pills, or herbal or dietary supplements.<\/li>\n\n\n\n<li>Do not take ACE inhibitors if you are pregnant or breastfeeding. Do not take these medicines if you are planning to become pregnant. Call your doctor if you become pregnant when you are taking these medicines.<\/li>\n<\/ul>\n\n\n\n<p class=\"wp-block-paragraph\"><em>*Note: The decision to prescribe a medication is the responsibility of your physician\/primary care provider based on his\/her evaluation of your condition. The above is meant for informational purposes only. Discuss this information and all information about drugs\/medications with your physician before starting or stopping any medication.<\/em><\/p>\n\n<\/div><\/div>\n<\/div>\n<\/div>\n<\/div>\n\n<div class=\"gb-container gb-container-0d21e4ac\">\n<div class=\"gb-grid-wrapper gb-grid-wrapper-3d338a55\">\n<div class=\"gb-grid-column gb-grid-column-296a2c84\"><div class=\"gb-container gb-container-296a2c84\">\n<div class=\"gb-container gb-container-eb83049f\">\n\n<h2 class=\"gb-headline gb-headline-5127a4de gb-headline-text\">Find a Specialist<\/h2>\n\n\n\n<p class=\"gb-headline gb-headline-00d5119d gb-headline-text\">It is important to work with a nephrologist who specializes in rare kidney disease (RKD) and can provide personalized advice based on your individual health needs and changes in available treatments. NephCure has a curated list of NephCure Specialists nationwide ready to help you.<\/p>\n\n<\/div>\n\n<div class=\"gb-container gb-container-54aa31c0\"><a class=\"gb-container-link\" href=\"https:\/\/nephcure.org\/managing-rkd\/find-a-specialist\/\"><\/a>\n\n<p class=\"gb-headline gb-headline-38137575\"><span class=\"gb-icon\"><svg fill=\"none\" viewBox=\"0 0 27 24\" height=\"24\" width=\"27\" xmlns=\"http:\/\/www.w3.org\/2000\/svg\"> <path fill=\"#00556B\" d=\"M26.0607 13.0607C26.6464 12.4749 26.6464 11.5251 26.0607 10.9393L16.5147 1.3934C15.9289 0.807611 14.9792 0.807611 14.3934 1.3934C13.8076 1.97919 13.8076 2.92893 14.3934 3.51472L22.8787 12L14.3934 20.4853C13.8076 21.0711 13.8076 22.0208 14.3934 22.6066C14.9792 23.1924 15.9289 23.1924 16.5147 22.6066L26.0607 13.0607ZM0 13.5H25V10.5H0V13.5Z\"><\/path> <\/svg><\/span><\/p>\n\n<\/div>\n<\/div><\/div>\n\n<div class=\"gb-grid-column gb-grid-column-00512214\"><div class=\"gb-container gb-container-00512214\">\n<div class=\"gb-container gb-container-178632bb\">\n\n<h2 class=\"gb-headline gb-headline-74b009b0 gb-headline-text\">Clinical Trials<\/h2>\n\n\n\n<p class=\"has-secondary-lighter-gray-color has-text-color has-link-color wp-elements-1 wp-block-paragraph\">From accessing cutting-edge treatments to being part of groundbreaking research, discover the benefits that can make a real difference. Learn more about clinical trials currently taking place, and find opportunities near you.<\/p>\n\n<\/div>\n\n<div class=\"gb-container gb-container-e263f928\"><a class=\"gb-container-link\" href=\"https:\/\/nephcure.org\/managing-rkd\/clinical-trials\/\"><\/a>\n\n<p class=\"gb-headline gb-headline-7dbd95e4\"><span class=\"gb-icon\"><svg fill=\"none\" viewBox=\"0 0 27 24\" height=\"24\" width=\"27\" xmlns=\"http:\/\/www.w3.org\/2000\/svg\"> <path fill=\"#00556B\" d=\"M26.0607 13.0607C26.6464 12.4749 26.6464 11.5251 26.0607 10.9393L16.5147 1.3934C15.9289 0.807611 14.9792 0.807611 14.3934 1.3934C13.8076 1.97919 13.8076 2.92893 14.3934 3.51472L22.8787 12L14.3934 20.4853C13.8076 21.0711 13.8076 22.0208 14.3934 22.6066C14.9792 23.1924 15.9289 23.1924 16.5147 22.6066L26.0607 13.0607ZM0 13.5H25V10.5H0V13.5Z\"><\/path> <\/svg><\/span><\/p>\n\n<\/div>\n<\/div><\/div>\n<\/div>\n<\/div>\n\n<div class=\"gb-container gb-container-42105b23 news-letter-sec alignfull\">\n\n<figure class=\"gb-block-image gb-block-image-b3f3ccb8\"><img loading=\"lazy\" decoding=\"async\" width=\"1920\" height=\"120\" class=\"gb-image gb-image-b3f3ccb8\" src=\"https:\/\/nephcure.org\/wp-content\/uploads\/2023\/11\/purple-curve.svg\" alt=\"\" title=\"purple-curve\"\/><\/figure>\n\n\n<div class=\"gb-container gb-container-41717e70 alignwide\">\n\n<h2 class=\"gb-headline gb-headline-1760ac29 gb-headline-text\">Sign up to get NephCure\u2019s latest updates.<\/h2>\n\n\n\n<a class=\"gb-button gb-button-753f318a gb-button-text gb-button-primary button\" href=\"\/newsletter\/\">SIGN UP<\/a>\n\n\n<div class=\"gb-container gb-container-2b968bcb news-letter-field\">\n    <script type=\"text\/javascript\">\n    jQuery(document).ready(function($) {\n        const disposableDomains = [\n            'mailinator.com', 'yopmail.com', 'tempmail.com', 'guerrillamail.com',\n            'throwawaymail.com', 'fakeinbox.com', 'trashmail.com', 'sharklasers.com',\n            'tempinbox.com', '10minutemail.com'\n        ];\n        const majorProviders = [\n            'gmail.com', 'yahoo.com', 'hotmail.com', 'outlook.com',\n            'aol.com', 'icloud.com', 'protonmail.com'\n        ];\n        const suspiciousUsernames = [\n            'test', 'example', 'user', 'admin', 'info', 'mail', 'email',\n            'noreply', 'no-reply', 'donotreply', 'do-not-reply', 'fake',\n            'abc', '123', 'xyz', 'asdf', 'qwerty', 'demo', 'sample',\n            'spam', 'temp', 'dummy', 'foobar', 'anonymous', 'disposable'\n        ];\n        const keyboardPatterns = ['qwerty', 'asdfgh', 'zxcvbn', '123456'];\n\n        function isValidEmailFormat(email) {\n            const regex = \/^[^\\s@]+@[^\\s@]+\\.[^\\s@]+$\/;\n            return regex.test(email);\n        }\n\n        function hasSuspiciousPattern(username) {\n            if (suspiciousUsernames.includes(username)) return true;\n            if (username.length <= 2) return true;\n            if (\/^(.)\\1{3,}$\/.test(username)) return true;\n            for (const pattern of keyboardPatterns) {\n                if (username.includes(pattern)) return true;\n            }\n            return false;\n        }\n\n        function usernameMatchesDomain(username, domain) {\n            const domainBase = domain.split('.')[0];\n            return username === domainBase;\n        }\n\n        $('.ginput_container_email input').on('blur', function() {\n            const emailField = $(this);\n            const email = emailField.val().trim().toLowerCase();\n            const errorContainer = emailField.siblings('.validation_message');\n\n            \/\/ Clear any previous messages\n            if (errorContainer.length) errorContainer.remove();\n            emailField.removeClass('gfield_error gfield_warning');\n\n            if (email === '') return;\n\n            const username = email.substring(0, email.lastIndexOf('@'));\n            const domain = email.substring(email.lastIndexOf('@') + 1);\n\n            if (!isValidEmailFormat(email)) {\n                emailField.after('<div class=\"validation_message\">Please enter a valid email address.<\/div>');\n                emailField.addClass('gfield_error');\n                return;\n            }\n\n            if (disposableDomains.includes(domain)) {\n                emailField.after('<div class=\"validation_message\">Disposable email addresses are not allowed.<\/div>');\n                emailField.addClass('gfield_error');\n                return;\n            }\n\n            if (usernameMatchesDomain(username, domain)) {\n                emailField.after('<div class=\"validation_message\">This email looks suspicious (username matches domain). 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